PROTEOMIC

作品数：227被引量：578H指数：13
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Multi-omics analysis reveals the epitranscriptomic and proteomic regulation network of tomato in low-temperature stress response
《Horticultural Plant Journal》2025年第2期758-773,共16页Na Wang Yanting Li Tianli Guo Libo Jiang 
financially supported by the National Natural Science Foundation of China(Grant Nos.32202518 and 32070601);Shandong University of Technology PhD Start-up Fund(418097)。
Tomato(Solanum lycopersicum)is an extensively cultivated vegetable,and its growth and fruit quality can be significantly impaired by low temperatures.The widespread presence of N^(6)-methyladenosine(m^(6)A)modificatio...
关键词：Epitranscriptome m^(6)A methylation PROTEOME Alternative polyadenylation Low temperature TOMATO 
Proteomic insights from extracellular vesicles into the molecular mechanisms of health effects induced by Per-and polyfluoroalkyl substances
《Journal of Environmental Sciences》2025年第4期395-411,共17页Yanping Li Yadan Luo Yang Liu Na Li Kai Huang Lingxiangyu Li Zhigang Li Chao Han Nali Zhu Yawei Wang Guibin Jiang 
supported by the Key Research and Development Plan of Zhejiang Province(No.2021C03176);Zhejiang Provincial Natural Science Foundation of China(No.LY23B070001);the Key Laboratory of Pollution Exposure and Health Intervention of Zhejiang Province(No.20230009);the National Natural Science Foundation of China(No.22106032);the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB0750000).
Per-and polyfluoroalkyl substances(PFASs)can induce a range of adverse health effects,with the precise molecularmechanisms remaining elusive.Extracellular vesicles(EVs)have demonstrated their potential to elucidate un...
关键词：Per-and polyfluoroalkyl substances Extracellular vesicles Health effects PROTEOMICS PROTEASOME 
Insights from a proteomic atlas of human Alzheimer's disease brain tissue
《Neural Regeneration Research》2025年第3期799-800,共2页Tomas Kavanagh Eleanor Drummond 
supported by the Bluesand Foundation;TDM Foundation;Faculty of Medicine and Health, University of Sydney (FMH EMCR Emerging Star Grant), NIH (P01AG060882) to ED。
There is an urgent need to identify new drug targets for Alzheimer's disease(AD). While new immunotherapies show promise, clinical benefit appears low, and side effects are high. A greater understanding of the disease...
关键词：ALZHEIMER CLINICAL driving 
Host-microbe computational proteomic landscape in oral cancer revealed key functional and metabolic pathways between Fusobacterium nucleatum and cancer progression
《International Journal of Oral Science》2025年第1期52-65,共14页Camila Paz Muñoz-Grez Mabel Angélica Vidal Tamara Beatriz Rojas Luciano Esteban Ferrada Felipe Andrés Zuñiga Agustin Andrés Vera Sergio Andrés Sanhueza Romina Andrea Quiroga Camilo Daniel Cabrera Barbara Evelyn Antilef Ricardo Andrés Cartes Milovan Paolo Acevedo Marco Andrés Fraga Pedro Felipe Alarcón-Zapata Mauricio Alejandro Hernández Alexis Marcelo Salas-Burgos Francisco Tapia-Belmonte Milly Loreto Yáñez Erick Marcelo Riquelme Wilfredo Alejandro González Cesar Andrés Rivera Angel Alejandro Oñate Liliana Ivonne Lamperti Estefanía Nova-Lamperti 
supported by Agencia Nacional de Investigación y Desarrollo(ANID),Chilean Government Fondecyt Regular 1211480;supported by a Master ANID Scholarship;funded by ANID/Fondecyt Regular 1211480;funded by EQM150061(FONDEQUIP-ANID)。
Oral squamous cell carcinoma(OSCC)is the most common manifestation of oral cancer.It has been proposed that periodontal pathogens contribute to OSCC progression,mainly by their virulence factors.However,the main perio...
关键词：METABOLISM HOST LANDSCAPE 
Genes and proteins expressed at different life cycle stages in the model protist Euplotes vannus revealed by both transcriptomic and proteomic approaches
《Science China(Life Sciences)》2025年第1期232-248,共17页Yaohan Jiang Xiao Chen Chundi Wang Liping Lyu Saleh A.Al-Farraj Naomi A.Stover Feng Gao 
supported by the Science&Technology Innovation Project of Laoshan Laboratory(LSKJ202203202);the National Natural Science Foundation of China(31922013,32270539);Natural Science Foundation of Shandong Province(ZR2020JQ13);Fundamental Research Funds for the Central Universities(202141004);the Researchers Supporting Project(RSP2024R7)King Saud University,Riyadh,Saudi Arabia.
Sexual reproduction first appeared in unicellular protists and has continued to be an essential biological process in almost all eukaryotes.Ciliated protists, which contain both germline and somatic genomes within a s...
关键词：sexual reproduction TRANSCRIPTOMIC PROTEOMIC genome rearrangement PIWI NHEJ 
Bakuchiol ameliorates glycolipid homeostasis by reducing inflammation
《Food Science and Human Wellness》2024年第6期3159-3170,共12页Zhenhua Liu Xiaoqing Xu Zhenhua Liang Yixiao Chen Qiuyi Wang Wenyi Kang Yan Zhang Bin Cong 
supported by National Key R&D Program of China(2022YFF1100300);the Central Guidance on Local Science and Technology Development Found of Shenzhen,China(2021Szvup030).
Inflammatory stimulation plays a significant role in the development and worsening of insulin-resistant diabetes.Therefore,it is crucial to identify therapeutic agents that can alleviate insulin resistance by targetin...
关键词：BAKUCHIOL DIABETES Insulin resistance PROTEOMIC INFLAMMATION 
DIA-based quantitative proteomic analysis on porcine meat quality at different chilling rates
《Food Science and Human Wellness》2024年第5期2573-2583,共11页Yuqiang Bai Tongjing Yan Fei Fang Xin Li Su Wang Juan Li Chengli Hou Dequan Zhang 
support from the National Natural Science Foundation of China(32030086).
The objective of this study was to evaluate the effects of chilling rate on porcine meat quality from the perspective of proteome using data independent acquisition(DIA)-based quantitative proteomic strategy. M. longi...
关键词：Very fast chilling TENDERNESS PROTEOMIC GLYCOLYSIS PROTEASOME 
Improvement of myocardial fibrosis injury by Shengmai injection in ischemia-induced heart failure in a rat model
《Science of Traditional Chinese Medicine》2024年第3期245-253,共9页Yurong Ding Junying Wei Enhui Ji Menglan Wang Yue Wu Mengli Chang Yi Zhang Jing Xu 
supported by the national key research and development program of China(2019YFC1708900);National Natural Science Foundation of China(82204973);scientific and technological innovation project of China Academy of Chinese Medical Sciences(CI2021B015);the fundamental research funds for the central public welfare research institutes of Institute of Chinese Materia Medica,China Academy ofChinese Medical Sciences(ZXKT21030);special program for outstanding,young scientific and technological talents(innovation)of China Academy of ChineseMedical Sciences(ZZ15-YQ-034).
Background:Heart failure(HF)is the leading cause of death worldwide.Myocardial infarction(MI)is a major contributor to HF.Shengmai injection(SMI)has exhibited protective efficacy in preventing HF.However,the advantage...
关键词：Shengmai injection Proteomic profile Heart failure Myocardial fibrosis Myocardial infarction 
Characterization of serum proteomic and inflammatory profiling at early stage of iron deficiency in weaned piglets被引量：1
《Animal Nutrition》2024年第3期380-389,共10页Guang Liu Lan Li Shuan Liu Zhenglin Dong Jian Zhou Chengyan Gong Yulong Yin Wenjie Tang Dan Wan 
supported by the National Key R&D Program of China(2022YFD1300504);the National Natural Science Foundation of China(32372827);the science and technology innovation Program of Hunan Prowince(2023RC3201);the Youth Innovation Promotion Association of Chinese Academy of Sciences(2022370).
The objective of this study was to examine the early serum proteomic and inflammatory profiles of weaned piglets subjected to iron deficiency.Twelve healthy piglets(Duroc×Landrace×Large Yorkshire,body weight:4.96±0...
关键词：PIGLET Iron deficiency Proteomics INFLAMMATORY CYTOKINE Immune response 
Circulating proteomic biomarkers for diagnosing sporadic amyotrophic lateral sclerosis:a cross-sectional study被引量：5
《Neural Regeneration Research》2024年第8期1842-1848,共7页Lu He Qinming Zhou Chaoyang Xiu Yaping Shao Dingding Shen Huanyu Meng Weidong Le Sheng Chen 
supported by the grants from Shanghai Shuguang Plan Project,No.18SG15(to SC);Shanghai Outstanding Young Scholars Project;Shanghai Talent Development Project,No.2019044(to SC);Medical-engineering cross fund of Shanghai Jiao Tong University,No.YG2022QN009(to QZ);the National Natural Science Foundation of China,No.82201558(to QZ)。
Biomarke rs are required for the early detection,prognosis prediction,and monitoring of amyotrophic lateral sclerosis,a progressive disease.Proteomics is an unbiased and quantitative method that can be used to detect ...
关键词：amyotrophic lateral sclerosis cathelicidin-related antimicrobial peptide HEMOGLOBIN label-free quantitative proteomics multi-protein combined diagnostic panel serum biomarkers talin-1 translationally-controlled tumor protein ZYXIN 
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