MADECASSOSIDE

作品数：5被引量：16H指数：2
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相关期刊：《Chinese Journal of Natural Medicines》《Plant Communications》《Advances in Alzheimer's Disease》《Asian Agricultural Research》更多>>
相关基金：国家自然科学基金更多>>
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The biosynthesis of asiaticoside and madecassoside reveals tandem duplication-directed evolution of glycoside glycosyltransferases in the Apiales被引量：1
《Plant Communications》2024年第10期166-179,共14页Xiaoyang Han Jingyi Zhao Hong Zhou Xuan Zhou Zixin Deng Zhenhua Liu Yi Yu 
supported by the Guangxi Science and Technology Base and Talent Special Project(AD23026030);the Guiding Funds of Central Government for Supporting the Development of the Local Science and Technology(ZY23055032);the National Natural Science Foundation of China(22277095)to Y.Y;Research in the Z.L.group is supported by a Key Project at the Central Government level:the Ability Establishment of Sustainable Use for Valuable Chinese Medicine Resources(2060302);the National Technologies Key R&D Program of China(2022YFC2602000)。
Certain plant species within the Apiales order accumulate triterpenoid saponins that feature a distinctive glucose-glucose-rhamnose(G-G-R)sugar chain attached at the C-28 position of the pentacyclic triterpene skeleto...
关键词：triterpenoid saponin glycoside glycosyltransferases BIOSYNTHESIS ASIATICOSIDE MADECASSOSIDE Centella asiatica 
Anti-inflammatory,Bacteriostatic and Anticancer Effects of Madecassoside
《Asian Agricultural Research》2023年第4期26-28,33,共4页Wenshuang HOU Jinglong CAO Jian LIU Hui XUE Yannan LI Chenghao JIN 
Supported by the Talent Training Program for the Reform and Development of Local Colleges and Universities of the Central Government(2020GSP16).
Madecassoside is a natural active component extracted from Centella asiatica.In recent years,a large number of studies have reported that madecassoside has a variety of biological activities,such as anticancer,anti-in...
关键词：MADECASSOSIDE Pharmacological effect Anti-inflammatory effect BACTERIOSTASIS Anticancer effect ARTHRITIS 
Madecassoside impedes invasion of rheumatoid fibroblast-like synoviocyte from adjuvant arthritis rats via inhibition of NF-κB-mediated matrix metalloproteinase-13 expression被引量：10
《Chinese Journal of Natural Medicines》2018年第5期330-338,共9页YU Wei-Guang SHEN Yong WU Jian-Zhong GAO Yan-Bing ZHANG Li-Xing 
Fibroblast-like synoviocytes(FLS) play a pivotal role in Rheumatoid arthritis(RA) pathogenesis through aggressive migration and invasion. Madecassoside(Madec), a triterpenoid saponin present in Centella asiatica herbs...
关键词：RHEUMATOID ARTHRITIS Fibroblast-like SYNOVIOCYTES MADECASSOSIDE Adjuvant-induced ARTHRITIS Matrix metalloproteinase-13 INVASION 
Confirmation of the Experimentally-Proven Therapeutic Utility of Madecassoside in an Aβ<sub>1-42</sub>Infusion Rat Model of Alzheimer’s Disease by in Silico Analyses
《Advances in Alzheimer's Disease》2015年第2期37-44,共8页Abdullah Al Mamun Michio Hashimoto Shahdat Hossain Masanori Katakura Hiroyuki Arai Osamu Shido 
The accumulation of amyloid β peptide 1 - 42 (Aβ1-42) in the brain of Alzheimer’s disease (AD) patients is known to be associated with neurodegeneration and memory impairment. More recently, we reported that madeca...
关键词：Alzheimer’s Disease CENTELLA asiatica MADECASSOSIDE AYURVEDA in Silico Drug Designing 
A LC-ESI-MS method for the simultaneous determination of madecassoside and its metabolite madecassic acid in rat plasma: comparison pharmacokinetics in normal and collagen-induced arthritic rats被引量：5
《Chinese Journal of Natural Medicines》2014年第12期943-951,共9页WANG Ting LENG Dan-Dan GAO Fei-Fei JIANG Chun-Jie XIA Yu-Feng DAI Yue 
financially supported by the National Natural Science Foundation of China(No.81374038,81173631);the Jiangsu Overseas Research&Training Program for University Prominent Young&Middle-aged Teachers and Presidents;sponsored by Qing Lan Project,College Students Innovation Project for the R&D of Novel Drugs(No.J1030830);partially funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions
To develop a simple and highly sensitive high performance liquid chromatography with electrospray ionization mass spectrometric(LC-ESI-MS) method for the simultaneous determination of madecassoside and its major metab...
关键词：MADECASSOSIDE Madecassic acid LC-ESI-MS PHARMACOKINETICS Collagen-induced arthritis 
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