INTERLEUKIN-1Β

作品数：160被引量：867H指数：15
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相关机构：山东大学中国科学技术大学四川大学华西医院中国科学院广州生物医药与健康研究院更多>>
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Ischemic stroke is an instigator of cardiac dysfunction:the interleukin-1βpathway
《Signal Transduction and Targeted Therapy》2024年第12期5373-5374,共2页Renate Schoenenberger-Berzins Andreas Janis Schoenenberger Franz H.Messerli 
In a recent study published in Cell,1 Simats et al.showed in a comprehensive series of elegant,mostly experimental studies,that stroke triggers epigenetic changes in innate immune cells which thereafter can affect the...
关键词：al. CARDIAC mostly 
Arctiin Protects Chondrocytes from Interleukin-1β-Induced Inflammation and Apoptosis by RNA Sequence In vivo and In vitro
《World Journal of Traditional Chinese Medicine》2024年第4期495-511,共17页Yong-Jia Song Jia-Min Bao Zeng-Qiao Zhang Yun-Xiang Hai Hao-Nan Wen Tian-Jun Zhai Wei Feng Min Song 
supported by the National Natural Science Foundation of China (81873328)
Objective:Osteoarthritis(OA) is a progressive joint disease characterized by degeneration and de struction of articular cartilage.Arctiin(ARC) has been shown in many studies to have potential anti-inflammatory,anti-ap...
关键词：APOPTOSIS ARCTIIN CHONDROCYTES INFLAMMATION OSTEOARTHRITIS RNA‑sequencing 
Analyze interleukin-1β,interleukin-6,and tumor necrosis factor-αlevels in dry eye and the therapeutic effect of cyclosporine A
《World Journal of Clinical Cases》2024年第25期5665-5672,共8页Juan Wu Gui-Jun Li Jie Niu Fei Wen Li Han 
BACKGROUND Dry eye is a common eye disease.Artificial tears supplements are widely used for the treatment of dry eyes.However,multiple adverse effects have been observed in patients receiving long-term treatment with ...
关键词：Artificial tears Dry eye syndrome CYCLOSPORINE Eye inflammation INTERLEUKIN-1Β INTERLEUKIN-6 Tumor necrosis factor-α Cyclosporine A 
Homer1a reduces inflammatory response after retinal ischemia/reperfusion injury被引量：1
《Neural Regeneration Research》2024年第7期1608-1617,共10页Yanan Dou Xiaowei Fei Xin He Yu Huan Jialiang Wei Xiuquan Wu Weihao Lyu Zhou Fei Xia Li Fei Fei 
supported by the Youth Development Project of Air Force Military Medical University,No.21 QNPY072;Key Project of Shaanxi Provincial Natural Science Basic Research Program,No.2023-JC-ZD-48(both to FF)。
Elevated intraocular pressure(IOP)is one of the causes of retinal ischemia/reperfusion injury,which results in NRP3 inflammasome activation and leads to visual damage.Homerla is repo rted to play a protective role in ...
关键词：CASPASE-8 Homer1a INTERLEUKIN-18 INTERLEUKIN-1Β intraocular pressure ischemia/reperfusion injury JSH-23 Müller cells NLRP3 nuclear factor-kB p65 RETINA 
Interleukin-1β:Friend or foe for gastrointestinal cancers
《World Journal of Gastrointestinal Oncology》2024年第5期1676-1682,共7页Kullanat Khawkhiaw Jutatip Panaampon Thanit Imemkamon Charupong Saengboonmee 
Supported by National Research Council of Thailand,No.N41A640108;Mekong-Lancang Cooperation Special Fund;The Development and Promotion of Science and Technology Talents Project;Ministry of Education,Science,Sports,and Culture of Japan,No.22K16327 and No.22K08482.
Gastrointestinal(GI)cancer is a malignancy arising in the digestive system and accounts for approximately a third of increasing global cancer-related mortality,especially in the colorectum,esophagus,stomach,and liver....
关键词：CANCER Gastrointestinal tract INFLAMMATION INTERLEUKIN-1Β Tumor microenvironment 
Teneligliptin mitigates diabetic cardiomyopathy by inhibiting activation of the NLRP3 inflammasome被引量：6
《World Journal of Diabetes》2024年第4期724-734,共11页Gu-Lao Zhang Yuan Liu Yan-Feng Liu Xian-Tao Huang Yu Tao Zhen-Huan Chen Heng-Li Lai 
Supported by National Natural Science Foundation of China,No.82000276;the Science and Technology Project of Jiangxi Provincial Health Commission,No.202310005.
BACKGROUND Diabetic cardiomyopathy(DCM),which is a complication of diabetes,poses a great threat to public health.Recent studies have confirmed the role of NLRP3(NOD-like receptor protein 3)activation in DCM developme...
关键词：Diabetic cardiomyopathy Teneligliptin NLRP3 AMPK INTERLEUKIN-1Β 
NLRP3 activation in macrophages promotes acute intestinal injury in neonatal necrotizing enterocolitis被引量：2
《World Journal of Pediatrics》2024年第2期153-164,共12页Bo Shi Cheng-Jie Lyu Zhen-Kai Le Hao-Sen Ji Yi Xiao Yuan-Yuan Zhang Shou-Jiang Huang Lin-Jun Yu Qiang Shu Jin-Fa Tou Deng-Ming Lai 
supported by the National Natural Science Foundation of China(81901989 to LDM,82272191 to SQ,and 82171699 to TJF);Natural Science Foundation of Zhejiang Province(LY21H150005 to LDM,LY22H040006 to TJF);Foundation for The Top-Notch Youth Talent Cultivation Project of Independent Design Project of National Clinical Research Center for Child Health(Q21B0007 to LDM);Special Fund for the Incubation of Young Clinical Scientist,Children's Hospital,Zhejiang University School of Medicine(CHZJU2022YS002 to LDM).
Background Macrophages are involved in various immune inflammatory disease conditions.This study aimed to investigate the role and mechanism of macrophages in regulating acute intestinal injury in neonatal necrotizing...
关键词：CASPASE-1 INTERLEUKIN-1Β MACROPHAGE Necrotizing enterocolitis NLRP3 
Suppressing high mobility group box-1 release alleviates morphine tolerance via the adenosine5'-monophosphate-activated protein kinase/heme oxygenase-1 pathway被引量：1
《Neural Regeneration Research》2023年第9期2067-2074,共8页Tong-Tong Lin Chun-Yi Jiang Lei Sheng Li Wan Wen Fan Jin-Can Li Xiao-Di Sun Chen-Jie Xu Liang Hu Xue-Feng Wu Yuan Han Wen-Tao Liu Yin-Bing Pan 
supported by the National Natural Science Foundation of China;Nos.81971047 (to WTL) and 82073910 (to XFW);the Natural Science Foundation of Jiangsu Province,No.BK20191253 (to XFW);Key R&D Program (Social Development) Project of Jiangsu Province,No.BE2019 732 (to WTL);Jiangsu Province Hospital (the First Affiliated Hospital of Nanjing Medical University) Clinical Capacity Enhancement Project,No.JSPH-511B2018-8 (to YBP)。
Opioids,such as morphine,are the most potent drugs used to treat pain.Long-term use results in high tolerance to morphine.High mobility group box-1(HMGB1) has been shown to participate in neuropathic or inflammatory p...
关键词：adenosine 5’-monophosphate-activated protein kinase heme oxygenase-1 high mobility group box-1 INTERLEUKIN-1Β MICROGLIA morphine tolerance NEUROINFLAMMATION neuron nuclear factor-κB p65 Toll-like receptor 4 
Serum basic fibroblast growth factor and interleukin-1βpredict the effect of first-line chemotherapy in patients with advanced gastric cancer
《World Journal of Clinical Cases》2023年第26期6083-6090,共8页Li Zheng Li-Hong Gan Ling Yao Bin Li Ya-Qin Huang Fu-Bao Zhang Meng-Qi Kuang Nian Fang 
Jiangxi Province Major Discipline Academic and Technical Leaders Project,No.812178084229.
BACKGROUND The incidence and mortality rates of gastric cancer in China are the second-highest in the world,and most patients with gastric cancer lose their chance of surgery by the time of their diagnosis.AIM To expl...
关键词：FLOT regimen SOX regimen Advanced gastric cancer First-line chemotherapy Tissue peptide-specific antigen 
Transcription and Secretion of Interleukin-1β and HMGB1 in Keratinocytes Exposed to Stimulations Mimicking Common Inflammatory Damages被引量：1
《International Journal of Dermatology and Venereology》2023年第3期121-129,共9页Xue-Cui Wei Yu-Jie Chen Fang-Yuan Long Shan-Shan Yu Song Xu Xu Chen 
supported by grants from the National Natural Science Foundation of China(81972952,81872531,82173438,and 82273550);Nanjing Incubation Program for National Clinical Research Center(2019060001);CAMS Innovation Fund for Medical Sciences(2021-1-I2M-059,2017-I2M-1-017);Jiangsu Province Foundation(LGY2018095,WSW-016);PhD Programs Foundation of Ministry of Education of China(No.20131106120046)
Objective:Interleukin-1β(IL-1β)and high-mobility group box 1(HMGB1)are widely known damage-associated molecular patterns(DAMPs).However,their expression and secretion in different skin diseases,especially in inflamm...
关键词：damage-associated molecular patterns INTERLEUKIN-1Β high-mobility group box 1 KERATINOCYTES inflammatory skin disorders 
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