INTERLEUKIN-18

作品数:81被引量:440H指数:13
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相关领域:医药卫生更多>>
相关作者:冯志山郭映辉赵瑞景张文超邵智利更多>>
相关机构:天津医科大学河北省儿童医院河北医科大学徐州医科大学更多>>
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相关基金:国家自然科学基金中国博士后科学基金国家重点基础研究发展计划河北省医学科学研究重点课题更多>>
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Homer1a reduces inflammatory response after retinal ischemia/reperfusion injury被引量:1
《Neural Regeneration Research》2024年第7期1608-1617,共10页Yanan Dou Xiaowei Fei Xin He Yu Huan Jialiang Wei Xiuquan Wu Weihao Lyu Zhou Fei Xia Li Fei Fei 
supported by the Youth Development Project of Air Force Military Medical University,No.21 QNPY072;Key Project of Shaanxi Provincial Natural Science Basic Research Program,No.2023-JC-ZD-48(both to FF)。
Elevated intraocular pressure(IOP)is one of the causes of retinal ischemia/reperfusion injury,which results in NRP3 inflammasome activation and leads to visual damage.Homerla is repo rted to play a protective role in ...
关键词:CASPASE-8 Homer1a INTERLEUKIN-18 INTERLEUKIN-1Β intraocular pressure ischemia/reperfusion injury JSH-23 Müller cells NLRP3 nuclear factor-kB p65 RETINA 
Analysis of the Role of D-Dimer,Interleukin-6,and Interleukin-18 in Differential Diagnosis of Pediatric Refractory Mycoplasma pneumoniae Pneumonia
《Journal of Clinical and Nursing Research》2024年第7期118-122,共5页Yong Peng Aimin Li 
Objective:To analyze the value of D-dimer(D-D),interleukin-6(IL-6),and IL-18 in the differential diagnosis of children with refractory Mycoplasma pneumoniae pneumonia(RMPP).Methods:The medical records of 92 children w...
关键词:Refractory Mycoplasma pneumoniae pneumonia D-DIMER INTERLEUKIN-6 INTERLEUKIN-18 Differential diagnosis 
Effects of Wenglian Jiedu decoction on expression of serum IL-18, TNF-α and MUC2 in colon tissue of ulcerative colitis rats
《Journal of Hainan Medical University》2022年第3期25-30,共6页Yu-Ting Lu Gui-Ye An Xiao-Yan Zhang Qian Yang Yong-Li Huo Dian-Gui Li 
Cooperative Pilot Project of Traditional Chinese Medicine and Western Medicine on Prevention and Treatment of Major Difficult Diseases(Ulcerative colitis)[(2018)No 3];Construction Project of Key Subject(Traditional Chinese Medicine)of National Administration of Traditional Chinese Medicine[(2018)No 210];Periodic Study on Effect of Combination of Shaoyao Decoction with Mesalazine on Rats with Ulcerative Colitis(No.2020077)。
Objective:To study the effect of Wenglian jiedu decoction on the expression of serum interleukin-18(IL-18),tumor necrosis factor-α(TNF--α)and colonic mucin-2(MUC2)in rats with ulcerative colitis of turbid toxin type...
关键词:Wenglian Jiedu decoction MESALAZINE INTERLEUKIN-18 Tumor necrosis factor-α Mucin-2 
Leukocyte telomere length and plasma interleukin-1β and interleukin-18 levels in mild cognitive impairment and Alzheimer's disease: new biomarkers for diagnosis and disease progression?被引量:3
《Neural Regeneration Research》2021年第7期1397-1398,共2页Rosa Maria Corbo Rita Businaro Daniela Scarabino 
supported by Sapienza University of Rome (2017/2018 grants allotted to RB and RMC)。
Alzheimer's disease and mild cognitive impairment biomarkers: Alzheimer's disease(AD) is a progressive neurodegenerative disease of advancing age.It affects around 47 million people in the world and the number is esti...
关键词:ALZHEIMER IMPAIRMENT DIAGNOSIS 
Association of interleukin-18 gene polymorphisms with Takayasu arteritis in a Chinese Han population被引量:3
《Chinese Medical Journal》2020年第19期2315-2320,共6页Dan Wen Xian-Liang Zhou Xin Du Jian-Zeng Dong Chang-Sheng Ma 
grants from the National Key Research and Development Program of China(No.2016YFC1301002 and No.2020YFC2004803);National Natural Science Foundation of China Grant(No.81900449).
Background:Interleukin-18(IL18)gene polymorphisms are related to many inflammatory and autoimmune diseases.However,a correlation analysis between IL18-607C/A and-137G/C gene polymorphisms and Takayasu arteritis(TA)is ...
关键词:Gene polymorphism INTERLEUKIN-18 Takayasu arteritis 
Interleukin-18 levels in the hippocampus and behavior of adult rat offspring exposed to prenatal restraint stress during early and late pregnancy
《Neural Regeneration Research》2020年第9期1748-1756,共9页Mo-Xian Chen Qiang Liu Shu Cheng Lei Lei Ai-Jin Lin Ran Wei Tomy C.K.Hui Qi Li Li-Juan Ao Pak C.Sham 
supported by the National Natural Science Foundation of China,No.81260296(to LJA)and 81300987(to QLi)
Exposure to maternal stress during prenatal life is associated with an increased risk of neuropsychiatric disorders, such as depression and anxiety, in offspring. It has also been increasingly observed that prenatal s...
关键词:BEHAVIOR depression dorsal hippocampus INTERLEUKIN-18 prenatal restraint stress recognition memory SEX ventral hippocampus 
Impact of IL-18 gene promoter polymorphisms on renal cell carcinoma occurrence and prognosis in Chinese Han population
《Oncology and Translational Medicine》2019年第6期278-284,共7页Shaojun Nong Yangbo Guan Zhongqing Wei Yueping Zhang Bin Cheng Chongsheng He Limin Ma Shujun Zhou Wenguang Li Jian Ni Zhiwei Wang 
Supported by grants from the China Postdoctoral Science Foundation(No.2014M139951);the Science and Technology Project of Nantong,Jiangsu Province(No.MS22016043)
Objective Genetic polymorphisms in various inflammatory cytokines have been associated with the risk and growth or invasiveness of renal cell carcinoma(RCC).However,the molecular basis of RCC pathogenesis is unclear.T...
关键词:INTERLEUKIN-18 renal cell carcinoma POLYMORPHISM PROGNOSIS 
Significant association between IL-18 and OCT4 gene polymorphisms in susceptibility and clinical characteristics of prostate cancer被引量:2
《Oncology and Translational Medicine》2019年第3期123-130,共8页Shaojun Nong Yangbo Guan Zhiwei Wang Zhongqing Wei Yueping Zhang Jian Ni Chongsheng He Limin Ma Shujun Zhou Wenguang Li 
Supported by grants from the China Postdoctoral Science Foundation(No.2014M139951);the Science and Technology Project of Nantong,Jiangsu Province(No.MS22016043)
Objective Recent studies have shown abnormal expression of octamer-binding transcription factor 4(OCT4) and interleukin-18(IL-18) to be related to cancer. However, the molecular mechanisms by which the IL-18 and OCT4 ...
关键词:clinical characteristics interleukin-18(IL-18) octamer-binding TRANSCRIPTION factor 4(OCT4) polymorphism prostate cancer 
Interleukin-18 exacerbates skin inflammation and affects microabscesses and scale formation in a mouse model of imiquimod-induced psoriasis被引量:10
《Chinese Medical Journal》2019年第6期690-698,共9页Xue-Li Niu Yu Huang Ya-Li Gao Yu-Zhe Sun Yang Han Hong-Duo Chen Xing-Hua Gao Rui-Qun Qi 
National Natural Science Foundation of China (Nos. 81673070, 81872538).
Background: As a potent pro-inflammatory cytokine of the interleukin (IL)-1 family, IL-18 was elevated in early active progressive plaque-type psoriatic lesions and that serum or plasma levels of IL-18 correlated with...
关键词:INTERLEUKIN-18 PSORIASIS CYTOKINES Scales 
Clinical study of IL-18 and NANOG gene polymorphisms in prostate cancer patients被引量:2
《Oncology and Translational Medicine》2018年第6期247-254,共8页Shaojun Nong Yangbo Guan Zhiwei Wang Zhongqing Wei Yueping Zhang Jian Ni Chongsheng He Limin Ma Shujun Zhou Wenguang Li 
Supported by grants from China Postdoctoral Science Foundation(No.2014M139951);The Science and Technology Project of Nantong,Jiangsu Province(No.MS22016043)
Objective Recent studies have shown abnormal expression of NANOG and IL-18 to be related to cancer. However, the molecular mechanism by which IL-18 and NANOG gene polymorphisms are associated with prostate cancer is u...
关键词:INTERLEUKIN-18 NANOG POLYMORPHISM PROSTATE cancer clinical characteristics 
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