非编码RNA在癫痫发病机制中的研究进展  

Advances of nocoding RNA in the mechanism of epilepsy

作　　者：赵午骏 黎瀚[1] 王彬 李少一[1] Zhao Wujun;Li Han;Wang Bin;Li Shaoyi(Department of Neurosurgery,Shengjing Hospital of China Medical University,Shenyang 110004,China;Department of Gynecology,Jining No.1 People′s Hosptital,Jining,Shangdong 272000,China)

机构地区：[1]中国医科大学附属盛京医院神经外科,沈阳110004 [2]山东省济宁市第一人民医院妇科,272000

出　　处：《中华神经科杂志》2021年第1期48-54,共7页Chinese Journal of Neurology

摘　　要：近年来越来越多的研究表明非编码RNA在癫痫的发生和发展过程中发挥了重要作用,并且参与了癫痫发病中的神经炎症、细胞凋亡和突触重塑等相关细胞过程。本综述重点介绍非编码RNA中的微小RNA、长链非编码RNA以及环状RNA与癫痫关系的最新研究进展。In recent years,a growing number of studies have shown that non-coding RNA plays an important role in the pathogenesis and development of epilepsy,and is involved in neuroinflammation,cell apoptosis,synaptic remodeling and cell differentiation in epilepsy.This review focused on the recent research progress in the relationship between microRNA,long-nocoding RNA and circular RNA with epilepsy.

关 键 词：癫痫 微小RNA 长链非编码RNA 环状RNA 

分 类 号：R742.1[医药卫生—神经病学与精神病学]