CT纹理分析对卵巢上皮肿瘤的鉴别诊断  

The differential diagnosis of CT texture analysis in ovarian epithelial tumor

作　　者：张懿 丁建平[1] ZHANG Yi;DING Jianping(Department of Radiology,The Affiliated Hospital of Hangzhou Normal University,Hangzhou 310015,P.R.China)

机构地区：[1]杭州师范大学附属医院放射科,浙江杭州310015

出　　处：《医学影像学杂志》2021年第2期293-296,301,共5页Journal of Medical Imaging

摘　　要：目的探讨基于CT平扫图像的纹理分析对鉴别卵巢上皮肿瘤良性、交界性及恶性的诊断价值。方法选取经病理证实的55例卵巢上皮肿瘤的术前CT图像和临床资料,其中良性、交界性及恶性肿瘤分别为21例、14例及20例。采用纹理分析软件于轴位CT平扫图像上提取病灶的纹理参数,各组间纹理参数比较采用独立样本t检验或Mann-Whitney U检验,对差异有统计学意义的纹理参数进行ROC曲线分析,评价其鉴别卵巢上皮肿瘤良性、交界性及恶性的诊断效能。结果恶性组的紧密度(Compactness)、熵(GlcmEntropy)高于交界性组,恶性组的熵(GlcmEntropy)、相对偏差(RelativeDeviation)高于良性组,均匀性(Uniformity)、表面积(SurfaceArea)、紧密度(Compactness)、立体像素值总和(VoxelValueSum)低于良性组,交界性组的均匀性低于良性组,差异均有统计学意义(P均<0.05)。ROC曲线显示部分纹理参数对卵巢上皮肿瘤各组间的诊断效能良好。结论基于CT平扫的部分纹理参数对鉴别卵巢上皮肿瘤的良性、交界性及恶性具有一定的临床价值,有利于临床对卵巢上皮肿瘤的早期诊断和干预。Objective To explore the value of CT texture analysis in the differential diagnosis of benign,borderline and malignant ovarian epithelial tumors.Methods The retrospective study was based on the preoperative CT images and clinical data of 55 cases of ovarian epithelial tumors,including 20 malignant tumors,14 borderline tumors and 21 benign tumors.The CT texture parameters of tumors were extracted using texture analysis software on the axis of CT scan images.An independent sample t-test or Mann-Whitney U test were used to compare the texture parameters among the groups,and the ROC analysis of the texture parameters with statistical significance was performed to evaluate the diagnostic efficacy of the texture parameters in differentiating benign,borderline and malignant ovarian epithelial tumors.Results The values of compactness and GlcmEntropy in malignant group were significantly higher than those in borderline group.The values of relative deviation and GlcmEntropy in malignant group were significantly higher than those in benign group.The values of uniformity,surface area,compactness and voxel value sum in malignant group were significantly lower than those in benign group.The value of Uniformity in borderline group was significantly lower than that in benign group.All the differences were statistically significant(all P<0.05).The results of ROC showed that some of the texture parameters’efficacy was effective in the diagnosis of ovarian epithelial tumor.Conclusion Some of the texture parameters based on CT plain scan have certain clinical value in differentiating benign,borderline and malignant ovarian epithelial tumors,which is conducive to early diagnosis and intervention of ovarian epithelial tumors.

关 键 词：卵巢上皮肿瘤 纹理分析 鉴别 体层摄影术 X线计算机 

分 类 号：R737.31[医药卫生—肿瘤] R814.42[医药卫生—临床医学]