2.4mm透明角膜切口超声乳化术后角膜生物力学的改变  

Corneal biomechanical alterations after phacoemulsitication with 2.4mm corneal incision

作　　者：杨军[1] 何宏[1] 陈晓莲[1] 丁辉[1] 钟兴武[1,2] Jun Yang;Hong He;Xiao-Lian Chen;Hui Ding;Xing-Wu Zhong(Hainan Eye Hospital Branch of Zhongshan Ophthalmic Center,Sun Yat-sen University,Key Laboratory of Ophthalmology in Hainan,Haikou 570311,Hainan Province,China;Zhongshan Ophthalmic Center,Sun Yat-sen University,National Key Laboratory of Ophthalmology,Guangzhou 510060,Guangdong Province,China)

机构地区：[1]中山大学中山眼科中心海南眼科医院海南省眼科医院海南省眼科学重点实验室,中国海南省海口市570311 [2]中山大学中山眼科中心国家眼科重点实验室,中国广东省广州市510060

出　　处：《国际眼科杂志》2021年第3期520-523,共4页International Eye Science

基　　金：国家自然科学基金面上项目(No.81870681);2017年海南省自然科学基金(No.2017CXTD011,817364)。

摘　　要：目的:运用Corvis ST研究2.4mm透明角膜切口白内障超声乳化术后1mo内角膜生物力学参数改变。方法:采用患者术眼术前术后自身对照研究。对2019-03/09符合纳入标准的28例56眼年龄相关性白内障患者进行2.4mm透明角膜切口白内障超声乳化抽吸+人工晶状体植入术。使用Corvist ST对28例患者术前1d,术后3、6d,1mo进行角膜生物力学测量比较。结果:受检眼术前术后第一次压平长度(A1L)、第二次压平时间(A2T)、中央角膜厚度(CCT)比较均有差异(F=10.534、11.655、14.734,均P<0.05)。术后3d测得A1L较术前及术后6d显著升高,A2T则显著降低(P<0.05)。术前1d与术后6d比较,A2L、A2T均无差异(P>0.05)。术后3、6d CCT大于术前1d(均P<0.05)。CCT在术后3d达到最大值,术后1mo恢复术前水平。结论:2.4mm透明角膜切口白内障超声乳化术后角膜生物力学参数发生变化,术后1mo各项参数基本恢复术前水平。AIM:To investigate the corneal biomechanical parameters alteration after phacoemulsitication with 2.4mm corneal incision within 1mo by Corvist ST.METHODS:A self control study was performed.Twenty-eight age related cataract patients(56 eyes),who were in accordance with the inclusion criteria,received phacoemulsification with 2.4mm corneal incision from March to September in 2019.Corneal biomechanical parameters were measured preoperatively and postoperatively on 3d,6d and 30d by Corvis ST.RESULTS:The first applanation length(A1L),the second applanation time(A2T)and corneal thickness(CCT)were significantly different between preoperation and postoperation(F=10.534,11.655,14.734;all P<0.05).The value of A1L on 3d postoperative was significantly increased than that on the day before operation,6d and 30d postoperative,while the A2T value was significantly reduced(P<0.05).But there was no different in A2L and A2T between preoperation and 6d postoperative(P>0.05).The value of central corneal thickness(CCT)was significantly increased on 3d and 6d postoperative compared with the preoperative parameter(P<0.05).The value of CCT got the maximum value on the 3d after surgery,and recovered to the preoperative level on the 30d after surgery.CONCLUSION:Phacoemulsitication with 2.4mm corneal incision change the corneal biomechanical preoperties.The corneal biomechanical parameters are basically recovered in the 30d postoperative.

关 键 词：角膜生物力学 白内障超声乳化术 可视化角膜力学分析仪 

分 类 号：R779.6[医药卫生—眼科]