同轴常规切口与微切口超声乳化术对白内障患者视力、角膜散光以及泪液炎性因子的影响  

The Effect of Phacoemulsification with Coaxial Conventional Incision and Micro Incision on Vision, Corneal Astigmatism and Tear Inflammatory Factors in Cataract Patients

作　　者：白雪 蒋玉惠 张俊霞 张妍春 任美侠 BAI Xue;JIANG Yu-hui;ZHANG Jun-xia;ZHANG Yan-chun;REN Mei-xia(Department of Ophthalmology,Yan'an Hospital of China Medical University/Yan'an People's Hospital,Yan'an,Shaanxi,716000,China;Department of Ophthalmology,Yangling Demonstration District Hospital,Yangling,Shaanxi,712100,China;Department of Ophthalmology,Guangren Hospital Affiliated to Xi'an Jiaotong University,Xi'an,Shaanxi,710021,China)

机构地区：[1]中国医科大学延安医院/延安市人民医院眼科,陕西延安716000 [2]杨凌示范区医院眼科,陕西杨凌712100 [3]西安交通大学附属广仁医院眼科,陕西西安710021

出　　处：《现代生物医学进展》2020年第23期4585-4588,4596,共5页Progress in Modern Biomedicine

基　　金：国家自然科学基金面上项目(81570558);陕西省自然科学基础研究计划项目(2015JM8408)。

摘　　要：目的:探讨同轴常规切口与微切口超声乳化术对白内障患者角膜散光、视力以及泪液炎性因子的影响。方法:选取2018年1月~2019年12月期间我院收治的白内障患者80例,根据随机数字表法分为对照组(n=40)和研究组(n=40),对照组患者采用同轴常规切口超声乳化术,研究组采用同轴微切口超声乳化术,比较两组患者术中前房稳定性、最佳矫正视力、平均超声能量、角膜散光程度、有效超声乳化时间、泪液炎性因子以及术后恢复时间,记录两组术后并发症发生率。结果:两组术后1d、术后1周、术后1个月、术后3个月最佳矫正视力呈升高趋势,且研究组高于对照组(P<0.05)。研究组术后1周、术后1个月、术后3个月角膜散光程度低于对照组(P<0.05)。两组患者有效超声乳化时间、平均超声能量、术中前房稳定人数占比比较差异无统计学意义(P>0.05);研究组术后恢复时间短于对照组(P<0.05)。两组术后3个月泪液白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)均下降,且研究组低于对照组(P<0.05)。两组术后并发症发生率比较差异无统计学意义(P>0.05)。结论:与同轴常规切口超声乳化术相比,同轴微切口超声乳化术治疗白内障患者,在改善患者角膜散光、视力以及泪液炎性因子水平方面效果显著,且不增加术后并发症发生率。Objective: To investigate the effect of phacoemulsification with coaxial conventional incision and micro incision on corneal astigmatism, vision and tear inflammatory factors in cataract patients. Methods: 80 cataract patients who were treated in our hospital from January 2018 to December 2019 were selected, they were randomly divided into two groups: control group(n = 40) and study group(n = 40). Patients in the control group were treated with coaxial conventional incision phacoemulsification, while patients in the study group were treated with coaxial micro incision phacoemulsification. Intraoperative anterior chamber stability, best corrected vision, average ultrasound energy, corneal astigmatism, effective phacoemulsification time, lacrimal inflammatory factors and postoperative recovery time in the two groups were compared, the incidence of postoperative complications was recorded. Results: The best corrected visual acuity of the two groups increased 1 d after operation, 1 week after operation, 1 month after operation, 3 months after operation, and the study group was higher than the control group(P < 0.05). The corneal astigmatism in the study group was lower than that in the control group at 1 week after operation, 1 month after operation, 3 months after operation(P< 0.05). There was no significant difference in the effective phacoemulsification time, average ultrasound energy and the proportion of patients with stable anterior chamber during operation between the two groups(P>0.05). The recovery time of the study group was shorter than that of the control group(P<0.05). The levels of Interleukin-6(IL-6), tumor necrosis factor-α(TNF-α) in lacrimal fluid of the two groups were lower than those of the control group(P < 0.05). There was no significant difference in the incidence of postoperative complications between the two groups(P > 0.05). Conclusion: Compared with the coaxial conventional incision phacoemulsification, the coaxial micro incision phacoemulsification can improve the corneal astigmatism, vi

关 键 词：常规切口 微切口 超声乳化术 白内障 视力 角膜散光 炎性因子 

分 类 号：R776.1[医药卫生—眼科]