腹腔镜逆行胆囊次全切除术对慢性胆囊炎伴胆囊结石患者体液免疫功能的影响  

Effect of Laparoscopic Retrograde Subtotal Cholecystectomy on Humoral Immune Function in Patients with Chronic Cholecystitis and Gallstone

作　　者：邓勇 Deng Yong(Department of Hepatobiliary Surgery,No.5 Affiliated Hospital of Guangzhou Medical University,Guangzhou 510700)

机构地区：[1]广州医科大学附属第五医院肝胆外科,广州510700

出　　处：《数理医药学杂志》2021年第3期333-335,共3页Journal of Mathematical Medicine

摘　　要：目的:观察腹腔镜逆行胆囊次全切除术对慢性胆囊炎伴胆囊结石患者体液免疫功能的影响。方法:将某院收治的60例慢性胆囊炎伴胆囊结石患者进行简单随机化分为对照组和观察组各30例。对照组行腹腔镜逆行胆囊全切除术,观察组行腹腔镜逆行胆囊次全切除术,对比两种术式的效果。结果:两组术后1周的IL-6和IgA值均较术前具有明显差异(P<0.05),但两组间无明显差异(P>0.05);观察组的术中出血量和手术时间均显著优于对照组(P<0.05)。结论:腹腔镜逆行胆囊次全切除术在不影响慢性胆囊炎伴胆囊结石患者体液免疫功能的情况下,具有术中出血量更少、手术时间更短的优势。Objective:To observe the effect of laparoscopic retrograde subtotal cholecystectomy on humoral immune function in patients with chronic cholecystitis and gallstone.Methods:60 patients with chronic cholecystitis and gallstone treated in a hospital were selected and randomly divided into two groups,with 30 cases in each group.Laparoscopic retrograde cholecystectomy was performed in the control group,and laparoscopic retrograde subtotal cholecystectomy was performed in the observation group,then the effect of the two methods were compared.Results:The IL-6 and IgA values of 1 week after operation in the two groups were significantly different before operation(P<0.05),but there was no significant difference between the two groups(P>0.05).The amount of bleeding and operation time in the observation group were significantly better than those in the control group(P<0.05).Conclusion:Laparoscopic retrograde subtotal cholecystecto my has the advantages of less bleeding and shorter operation time without affecting the humoral immune function of patients with chronic cholecystitis and gallstone.

关 键 词：慢性胆囊炎伴胆囊结石 腹腔镜逆行胆囊次全切除术 免疫功能 炎症介质 

分 类 号：R575.61[医药卫生—消化系统]