白蛋白、总蛋白、血红蛋白在宫颈癌患者中检测的临床意义及对预后的影响  

Clinical significance of ALB,TP and Hb detection in patients with cervical cancer and its influence on prognosis

作　　者：朱士杰[1] 陈红舟[2] 周晓[3] ZHU Shi-jie;CHEN Hong-zhou;ZHOU Xiao(Obstetrics and Gynecology,Zhoushan Hospital,Zhoushan,Zhejiang 316000,China;不详)

机构地区：[1]浙江省舟山医院妇产科,浙江舟山316000 [2]浙江省舟山医院妇科,浙江舟山316000 [3]浙江省舟山市妇幼保健院妇科,浙江舟山316000

出　　处：《中国卫生检验杂志》2021年第3期335-337,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的探讨白蛋白(ALB)、总蛋白(TP)及血红蛋白(Hb)在宫颈癌患者中检测的临床意义及对预后的影响。方法选择2009年3月-2014年6月在本院接受手术治疗的宫颈癌患者70例作为观察组,并同期选取70例体检健康者作为对照组,回顾性分析其临床资料,记录2组ALB、TP及Hb水平。另以ALB水平35 g/L为标准,将观察组患者分为低蛋白组及正常组,分析白蛋白水平与宫颈癌患者临床病理特征的关系及其对患者预后的影响结果观察组ALB,TP及Hb含量显著低于对照组(P<0.05);ALB水平与宫颈癌患者的肿瘤直径、发生淋巴结转移及肌层浸润深度显著相关(P<0.05),而ALB水平与宫颈癌患者的年龄.FIGO分期及HPV感染无关(P>0.05);低蛋白组3年及5年存活率均明显低于正常组(P<0.05)。结论宫颈癌患者营养状态较为低下,其ALB水平与肿瘤直径、发生淋巴结转移及肌层浸润深度显著相关,ALB水平越高患者预后越好。Objective To investigate the clinical significance of albumin( ALB),total protein( TP) and hemoglobin( Hb)detection in patients with cervical cancer and its influence on prognosis. Methods Seventy patients with cervical cancer who underwent surgical treatment in our hospital from March 2009 to June 2014 were selected as the observation group,and 70 healthy persons were selected as the control group during the same period. Their clinical data were retrospectively analyzed,and the serum levels of ALB,TP and Hb were recorded. In addition,according to the ALB level of 35 g/L,the patients in the observation group were divided into low protein group and normal group. The relationship between albumin level and clinicopathological characteristics of cervical cancer patients was analyzed,and the effect of albumin level on the prognosis of patients was analyzed. Results The contents of ALB,TP and Hb in the observation group was significantly lower than that in the control group( P < 0. 05). The ALB level was significantly correlated with the tumor diameter,lymph node metastasis and muscle layer infiltration depth of cervical cancer patients( P < 0. 05),while the ALB level was not significantly correlated with age,FIGO stage and HPV infection of cervical cancer patients( P > 0. 05). The 3-year and 5-year survival rates in the low protein group were significantly lower than those in the normal group( P < 0. 05). Conclusion The nutritional status of cervical cancer patients is relatively low,and their ALB level is significantly correlated with the tumor diameter,lymph node metastasis and the depth of muscle layer infiltration. The higher the ALB level,the better the prognosis of patients.

关 键 词：宫颈癌 白蛋白 临床病理特征 预后 

分 类 号：R737.33[医药卫生—肿瘤]