左束支区域起搏的研究进展  

Research progress of left bundle branch area pacing

作　　者：李琴瑶 龙开超[1] 张青海 唐毅[1] 钟常青[1] Li Qinyao;Long Kaichao;Zhang Qinghai;Tang Yi;Zhong Changqing(Department of Internal Medicine-Cardiovascular,the First Affiliated Hospital of Hunan Normal University(Hunan Provincial People's Hospital),Clinical Medical Research Center for Heart Failure of Hunan Province,Changsha 410000,China)

机构地区：[1]湖南师范大学附属第一医院(湖南省人民医院)心血管内科,湖南省心力衰竭临床医学研究中心,长沙410000

出　　处：《中国医师杂志》2021年第2期314-317,共4页Journal of Chinese Physician

基　　金：湖南省卫生健康委科研计划项目(20201209)。

摘　　要：传统右心室非生理性起搏可导致室内和室间电机械不同步,进而增加心力衰竭和心房颤动的风险。希氏-浦肯野系统起搏是生理性起搏的研究热点。希氏束起搏的阈值高、植入困难等因素限制了其应用和普及。近年来,国内学者提出了左束支区域起搏(LBBP)方式。且大量研究已证实左束支起搏的安全性和可行性。左束支起搏沿着传导系统下传,有效实现心室的电机械同步,同时,左束支起搏还具有电学参数良好稳定、明显改善心功能、可跨越阻滞部位起搏等诸多优势,将成为未来生理性起搏的重要发展方向。本文旨在对LBBP的起源、标准及分类、优势和局限性等进行综述。Traditional right ventricular pacing is non-physiological pacing,can lead to ventricular electrical and mechanical dyssynchmnization,which increases the risk of heart failure and atrial fibrillation.His-Purkinje system pacing is the hot research of physiological pacing method.The high thresholds and difficult implantation of his bundle pacing limits its application and popularization.In recent years,domestic scholars have proposed left bundle branch area pacing.Many studies have confirmed the safety and feasibility of left bundle branch area pacing.Left bundle branch pacing transmit down the conduction system,which can effectively achieve ventricular electrical and mechanical synchrony,At the same time,it also has many others advantages,such as good and stable electrical parameters,significantly improved cardiac function,and pacing across blocked parts.It will become the main development direction of physiological pacing in the future.This article aims to review the origin,standard and classification,advantages and limitations of left bundle branch area pacing.

关 键 词：左束支传导阻滞 生理性起搏 左束支区域起搏 

分 类 号：R541.7[医药卫生—心血管疾病]