角膜塑形镜对青少年近视角膜透明度的影响远期随访研究  

Long-term follow-up study on the effect of orthokeratology on corneal transparency of juvenile myopia

作　　者：郑祥丽 徐颖 Zheng Xiang-li;Xu Ying(Department of Ophthalmology,Chongqing Emergency Medical Center,Chongqing 400010,China)

机构地区：[1]重庆市急救医疗中心(重庆市第四人民医院)眼科,400010

出　　处：《中国斜视与小儿眼科杂志》2020年第4期17-20,共4页Chinese Journal of Strabismus & Pediatric Ophthalmology

基　　金：重庆市卫生和计划生育委员会医学科研项目(2015MDXM022)。

摘　　要：目的研究角膜塑形镜对青少年近视角膜透明度的影响及远期随访结果。方法收集2018年1月至2019年12月青少年近视者92例为研究对象,分为观察组(角膜塑形镜组,46例46眼)与对照组(框架眼镜组,46例46眼),随访1年,观察两组裸眼视力、屈光度、前后表面屈光率半径、前房深度及角膜并发症,利用Pentacam角膜地形图检测观察组患者角膜中央光学区与旁中央反转弧区角膜光密度值,评估角膜塑形镜对青少年近视患者角膜透明度的影响。结果与同组佩戴前比较,观察组裸眼视力、屈光度及前表面屈光率半径均显著上升(P<0.05),但后表面屈光率半径及前房深度无显著性改变(P>0.05);对照组佩戴前后裸眼视力、屈光度、前/后表面屈光率半径及前房深度均无显著性改变(P>0.05);观察组佩戴角膜塑形镜后一年,裸眼视力、屈光度、前表面屈光率半径均显著高于对照组(P<0.05);对照组佩戴框架眼镜未出现明显不适感,观察组佩戴角膜塑形镜期间,8眼出现角膜点染,均为1~2级,停戴2~5d后好转;视觉异常11眼,经调片后好转;2眼出现过敏性结膜炎,应用过敏药物更换润滑液后好转;观察组佩戴角膜塑形镜前与佩戴1年后,中央光学区与中央反转弧区光密度值均无显著性改变(P>0.05)。结论角膜塑形镜能有效改善青少年近视患者裸眼视力、屈光度及前表面屈光率半径,且长期效果稳定,长期佩戴不会对患者角膜光密度值产生影响。Objective To investigate the long-term effect of orthokeratology on corneal transparency of juvenile myopia.Methods A total of 92 cases of juvenile myopia in our hospital from January 2018 to December 2019 were enrolled,and divided into two groups,each with 46 patients(46 eyes).Observation group received orthokeratology lens,while control group received glasses.All patients were followed up for one year.Uncorrected visual acuity,diopter,anterior and posterior corneal surface curvature radius,anterior chamber depth and corneal complications were observed,meanwhile,the corneal optical density of central zone and paracentral reveres zone was also detected by Pentacam corneal topography.Then the effect of orthokeratology on corneal transparency in adolescents with myopia was evaluated.Results Comparison within observation group showed that there was an increase in the uncorrected visual acuity,diopter,and anterior corneal surface curvature radius(P<0.05),and no significant change in posterior corneal surface curvature radius and anterior chamber depth after treatment(P>0.05),while the uncorrected visual acuity,diopter,anterior and posterior corneal surface curvature radius,and anterior chamber depth of control remained unchanged after treatment(P>0.05).One year after wearing,the uncorrected visual acuity,diopter,and anterior corneal surface curvature radius of observation group was higher than that of control group(P<0.05).During the lens wearing,eyes in control group showed no significant discomfort;in observation group,8 eyes showed dyed cornea of grade 1~2,11 eyes showed visual abnormalities,and 2 eyes showed allergic conjunctivitis,and all of them were improved after symptomatic treatment;The corneal optical density of central zone and paracentral reveres zone at 1 year after wearing showed no significant difference with that before wearing(P>0.05).Conclusion Orthokeratology can effectively improve the uncorrected visual acuity,diopter,and anterior corneal surface curvature radius of adolescent myopia patients,wi

关 键 词：角膜塑形镜 青少年近视 角膜透明度 

分 类 号：R778.11[医药卫生—眼科]