苏云金芽孢杆菌杀蚊菌株研究进展  

Advances Research on Bacillus thuringiensis Mosquitocidal Strains

作　　者：周燕 朱英芝 姜明国 Zhou Yan;Zhu Yingzhi;Jiang Mingguo(Guangxi Key Laboratory for Polysaccharide Materials and Modifications,School of Marine Sciences and Biotechnology,Guangxi University for Nationalities,Nanning,530008)

机构地区：[1]广西民族大学海洋与生物技术学院,广西多糖材料与改性重点实验室,南宁530008

出　　处：《基因组学与应用生物学》2020年第10期4614-4623,共10页Genomics and Applied Biology

基　　金：广西科技基地和人才专项(桂科AD18281066);广西科技重大专项(桂科AA18242026);2018年度广西高校中青年教师基础能力提升项目2018KY0177共同资助。

摘　　要：苏云金芽孢杆菌作为生物杀虫剂已有近百年历史,其杀虫谱包括从鳞翅目、鞘翅目、膜翅目、双翅目到线虫甚至是癌症细胞,对农林业生产以及医学领域研究具有非常重要的作用。全球每年死于蚊媒疾病的数目惊人。本综述首先介绍了首个被发现对双翅目幼虫具有杀蚊活性的苏云金芽孢杆菌以色列亚种,详细叙述了该菌株的杀虫功能、菌株特点以及含有的多种杀虫毒蛋白基因;随后概述了报道的其他杀蚊菌株和杀蚊毒蛋白;还揭示了苏云金芽孢杆菌杀蚊菌株Cry/Cyt杀蚊毒蛋白的作用模式,为有关苏云金芽孢杆菌杀蚊菌株的研究提供借鉴。Bacillus thuringiensis has been used as a biological insecticide nearly 100 years,and its insecticidal spectrum including Lepidoptera,Coleoptera,Hymenoptera,Diptera,Nematodes and even cancer cells.It has a very important role in agricultural,forestry production and medical research.The number of death from mosquito-borne diseases every year in the world is staggering.Here,we firstly introduced Bacillus thuringiensis subsp.israelensis,the first strain found insecticidal activity against Diptera larvae,and then described its insecticide function,strain characteristics as well as its insecticidal protein genes in detail.Subsequently,summarized other mosquito-killing strains and mosquitocidal toxic proteins,finally,we also comprehensively revealed the mode action of Cry/Cyt mosquitocidal toxins of Bacillus thuringiensis strains,which provided a reference for the investigation of Bacillus thuringiensis mosquitocidal strains.

关 键 词：苏云金芽孢杆菌 杀蚊菌株 BTI 毒蛋白 杀蚊作用模式 

分 类 号：S476.1[农业科学—农业昆虫与害虫防治]