肝硬化自发性细菌性腹膜炎重症感染的临床综合分析  

Clinical Analysis of Severe Infection of Spontaneous Bacterial Peritonitis in Cirrhosis

作　　者：李建明 赵红玉 唐中权 LI Jian-ming;ZHAO Hong-yu;TANG Zhong-quan(Hepatoenterology Department,Hohhot Second Hospital,Hohhot 010031 China;Traditional Chinese Medicine Department,Hohhot Maternal and Child Health Hospital,Hohhot 010031 China)

机构地区：[1]呼和浩特市第二医院肝病消化科,内蒙古呼和浩特010031 [2]呼和浩特市妇幼保健医院中医科,内蒙古呼和浩特010031

出　　处：《内蒙古医学杂志》2020年第12期1409-1411,共3页Inner Mongolia Medical Journal

摘　　要：目的探讨肝硬化SBP重症感染的临床特征,以提高临床对SBP重症感染早期的认知度。方法收集98例肝硬化SBP患者,依据病情分为SBP普通感染组(普通组)51例和SBP重症感染组(重症组)47例。本资料通过两组患者入院首次的检测结果(阳性菌群、WBC、PA、ALB、CRP、PCT)和临床转归进行对比分析。结果 98例患者中,病原菌培养阳性率为13.2%,其中普通组5.8%、重症组21.3%,差异有统计学意义(χ^(2)=5.241,P=0.022),革兰阴性杆菌84.6%,革兰阳性球菌15.4%。两组WBC定性、定量和CRP、PCT定性检测,差异无统计学意义(P>0.05),两组PA、ALB、CRP、PCT定量检测,差异有统计学意义(P<0.01)。两组病死率为11.7%和29.8%,差异有统计学意义(χ^(2)=4.891,P=0.027)。结论肝硬化SBP重症感染患者的病死率高,病原菌以革兰阴性杆菌为主,检测PA、CRP、PCT有利于肝硬化SBP重症感染的早期诊断。Objective To improve the early recognition of Cirrhosis SBP severe infection, the clinical features of SBP severe infection is discussed.Methods According to the patients’ condition, 98 cases with cirrhosis SBP were divided into SBP general infection group(general group) 51 cases and SBP severe infection group(severe group) 47 cases. The data was obtained by comparative analyzing with the first test results(positive bacteria, WBC, PA, ALB, CRP, PCT) and clinical outcome of the cases.Results Among the 98 cases, the positive rate of pathogen culture is 13.2%, including 5.8% in the general group, 21.3% in the severe group(χ2=5.241,P=0.022), Gram-negative bacilli is 84.6%, and in Gram-positive cocci is 15.4%. There are no significant differences in qualitative,quantitative and CRP and PCT qualitative tests between the two groups(P>0.05),and significant differences in the quantitative detection of PA, ALB, CRP and PCT(P<0.01).The fatality rates are 11.7% and 29.8% in the two groups(χ2=4.891,P=0.027).Conclusion Patients with Cirrhosis SBP severe infection have a high mortality rate. Gram-negative are the main the pathogens bacilli. It was beneficial to early diagnosis of severe SBP infection of cirrhosis with detection of PA, CRP and PCT.

关 键 词：肝硬化 自发性细菌性腹膜炎 重症感染 病原菌 实验室检测 

分 类 号：R572[医药卫生—消化系统]