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作 者:柴佳威 朱坤兵 李亚琼 王甜甜 CHAI Jiawei;ZHU Kunbing;LI Yaqiong;WANG Tiantian(Department of Breast and Thyroid Surgery,Shandong Maternity and Child Care Hospital Affiliated to Shandong University,Jinan 250014,Shandong,China;Department of Pathology,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,Shandong,China;Department of Breast and Thyroid Surgery,Shandong Provincial Hospital Affiliated tol Shandong First Medical University,Jinan 250021,Shandong,China)
机构地区:[1]山东大学附属山东省妇幼保健院乳腺甲状腺外科,山东济南250014 [2]山东第一医科大学附属山东省立医院病理科,山东济南250021 [3]山东第一医科大学附属山东省立医院乳腺甲状腺外科,山东济南250021
出 处:《山东大学学报(医学版)》2021年第1期83-87,共5页Journal of Shandong University:Health Sciences
基 金:山东省医药卫生科技发展计划(2017ws098)。
摘 要:目的探讨隐匿性甲状腺癌病灶隐匿的可能原因,分析隐匿性甲状腺癌的临床特点及相关的治疗方式。方法对我科1例隐匿性甲状腺癌(中央区淋巴结查见甲状腺癌病灶,而甲状腺癌病理未证实原发灶)患者进行病例讨论,并通过文献复习,分析总结隐匿性甲状腺癌的病灶可能的隐匿原因、分类、诊断及治疗。结果经分析病例并文献检索,隐匿性甲状腺癌常见病灶隐匿原因:异位甲状腺组织的恶变、病理检测手段的局限、癌细胞的退行性改变。隐匿性甲状腺癌诊断相对困难,需综合应用多元化诊断手段来提高确诊率,治疗方式为以手术为主的综合治疗。本例患者随访20个月,无疾病进展。结论了解各类隐匿性甲状腺癌的临床特征、病灶可能的隐匿原因、诊断方法、以及手术方式,可以提高隐匿性甲状腺癌的确诊率并改善预后。Objective To explore the possible causes, clinical characteristics and treatment of occult thyroid carcinoma. Methods The clinical data of a case of occult thyroid carcinoma treated in our department were retrospectively analyzed and literature was reviewed. The etiology, classification, diagnosis and treatment of this rare disease were summarized. Results The possible causes of occult thyroid carcinoma included malignant transformation of ectopic thyroid tissues, limitations of pathological detection and degenerative changes of cancer cells. This disease was difficult to diagnose, and comprehensive methods were necessary to establish the diagnosis. Surgery was the major treatment. During the follow-up of 20 months, there was no disease progression in this case. Conclusion Understanding the clinical features, possible causes, diagnostic methods and surgical methods of all subtypes of occult thyroid carcinoma can improve the diagnosis rate and prognosis.
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