静脉和皮下自控镇痛在难治性癌痛中的治疗进展  

Progress of patient-controlled subcutaneous or intravenous analgesia in the treatment of intractable cancer pain

作　　者：金玉龙 吴密璐[1] 张宁 刁银卓 吴静 JIN Yulong;WU Milu;ZHANG Ning;DIAO Yinzhuo;WU Jing(Department of Oncology,Affiliated Hospital of Qinghai University,Xining,Qinghai,810001,China;Graduate School of Qinghai University,Xining,Qinghai,810001,China)

机构地区：[1]青海大学附属医院肿瘤内科,青海西宁810001 [2]青海大学研究生院,青海西宁810001

出　　处：《当代医学》2021年第10期191-194,共4页Contemporary Medicine

摘　　要：患者自控镇痛(patient-controlled analgesia,PCA)技术主要用于治疗难治性癌痛和爆发痛,及阿片类药物的剂量滴定和快速调整。PCA突出给药的独特优势,根据患者的个体情况,预先设置给药参数,由患者"主动参与"和"自我管理"的镇痛技术。PCA可维持稳定的血药浓度并有效镇痛,及时治疗爆发痛。该技术由医护人员根据患者身体一般情况和疼痛程度,预先设置镇痛药物剂量及止痛泵参数,再交由患者"自我管理"的一种疼痛控制技术。其能完成快速的剂量滴定,快速缓解疼痛,并能适应个体化的镇痛需求,是微创治疗癌痛的良好选择,本文就静脉和皮下自控镇痛在难治性癌痛中的治疗进展进行综述。Patient-controlled intravenous and subcutaneous analgesia are mainly used for dose titration,refractory cancer pain and outburst pain of opioids.Patient-controlled analgesia technique is to autonomously control the analgesic method of drug administration through the calculation of analgesic drug dosage by medical staff and the setting of analgesic pump parameters.It is a good choice for minimally invasive treatment of cancer pain because it can complete rapid dose titration,relieve pain quickly,and can adapt to the needs of individual analgesia.In this paper,the progress of intravenous and subcutaneous controlled analgesia in the treatment of refractory cancer pain is reviewed.

关 键 词：难治性癌痛 患者自控皮下和静脉自控镇痛 吗啡 氢吗啡酮 舒芬太尼 

分 类 号：R730.5[医药卫生—肿瘤]