经腹腔镜保留肾单位肿瘤切除术治疗T2期肾癌对患者肾功能及预后的影响观察  

Effects of Laparoscopic Nephron-Sparing Tumor Resection on Renal Function and Prognosis in Patients With Stage T2 Renal Cancer

作　　者：柳林 沙文[1] 纪传彪 芦才广 马鹏德 武新威 Liu Lin;Sha Wen;Ji Chuanbiao;Lu Caiguang;Ma Pengde;Wu Xinwei(Department of Urology,Puyang Oilfield General Hospital,Puyang 457000,China)

机构地区：[1]濮阳市油田总医院泌尿外科,河南濮阳457000

出　　处：《哈尔滨医药》2021年第1期20-22,共3页Harbin Medical Journal

摘　　要：目的观察经腹腔镜保留肾单位肿瘤切除术(LNSS)治疗T2期肾癌对患者肾功能及预后的影响。方法选取70例T2期肾癌患者为研究对象,按随机数表法分为观察组与对照组各35例。对照组实施开放性手术方式,观察组实施LNSS。比较术前及术后7d时两组患者肾功能指标[尿素氮(BUN)、血肌酐(SCr)]变化,分析两组患者手术情况(手术时间、术后引流管留置时间、术后住院时间)及术后7d内并发症发生情况、术后1年预后情况(复发率、生存率)差异。结果术后7d时,两组患者BUN与SCr较手术前有明显提高,且观察组明显低于对照(P<0.05);两组患者手术时间、术后引流管留置时间、术后住院时间观察组明显低于对照组(P<0.05);术后7d内,术后并发症及总发生率比较均无统计学意义(P>0.05)。术后1年时,两组患者复发率及生存率比较均无统计学意义(P>0.05)。结论通过LNSS治疗T2期肾癌患者利于其术后康复,对患者肾功能恢复及改善预后有利。Objective To observe the effects of laparoscopic nephron-sparing surgery(LNSS)on renal function and prognosis of patients with stage T2 renal cancer.Methods A total of 70 patients with stage T2 renal cancer treated were selected as the research subjects,and they were divided into observation group and control group according to the random number table method,with 35 cases in each group.Control group underwent open surgery,and observation group underwent LNSS.The changes of renal function indexes[urea nitrogen(BUN),blood creatinine(SCr)]were compared between the two groups before surgery and at 7d after surgery.The surgical status(operative time,postoperative drainage tube indwelling time,postoperative hospital stay),occurrence of complications within 7d after surgery and prognosis(recurrence rate,survival rate)at 1 year after surgery were analyzed in the two groups.Results At 7d after surgery,the BUN and SCr in the two groups were significantly improved compared with those before surgery,and the indexes in observation group were significantly lower than those in control group(P<0.05).The operative time,postoperative drainage tube indwelling time and postoperative hospital stay in observation group were significantly lower than those in control group(P<0.05).Within 7d after surgery,there were no statistically significant differences in the incidence rates of postoperative complications and the overall incidence rate(P>0.05).At 1 year after surgery,there were no statistically significant differences in the recurrence rate and survival rate between the two groups(P>0.05).Conclusion LNSS for patients with stage T2 renal cancer is beneficial to the postoperative recovery,and is beneficial to the recovery of renal function and the improvement of prognosis.

关 键 词：腹腔镜 肾单位 肿瘤切除术 T2期肾癌 肾功能 预后 

分 类 号：R730.56[医药卫生—肿瘤]