99Tcm-奥曲肽眼眶显像联合MRI在TAO分期诊断中的效能  

Efficacy of 99Tcm-Octreotide orbital imaging combined with MRI in stage diagnosis of TAO

作　　者：程果 孔维倩 岳毅明 Guo Cheng;Wei-Qian Kong;Yi-Ming Yue(Department of Medical Image, the First Affiliated Hospital of Nanyang Medical College, Nanyang 473000, Henan Province, China)

机构地区：[1]中国河南省南阳市医学高等专科学校第一附属医院医学影像科,473000

出　　处：《国际眼科杂志》2021年第4期722-725,共4页International Eye Science

摘　　要：目的:探讨99Tcm-奥曲肽眼眶显像联合核磁共振成像(MRI)在甲状腺相关性眼病(TAO)分期诊断中的效能。方法:回顾性分析2017-06/2018-06收治的35例接受手术治疗的TAO患者的临床资料,均行99Tcm-奥曲肽眼眶显像联合MRI检查,手术取材进行病理学观察,并进行病理分期。统计病理分期结果,观察99Tcm-奥曲肽眼眶显像联合MRI检查的影像学表现和结果,分析99Tcm-奥曲肽眼眶显像、MRI、99Tcm-奥曲肽眼眶显像联合MRI检查对TAO分期诊断的效能。结果:35例TAO患者共58眼患病,经病理分期为活动期(49眼)、非活动期(9眼);99Tcm-奥曲肽眼眶显像和MRI诊断TAO分期均有典型影像学表现,且99Tcm-奥曲肽眼眶显像联合MRI诊断活动期TAO的灵敏度、特异度、准确度均高于单独应用99Tcm-奥曲肽眼眶显像、MRI检查,且ROC结果显示99Tcm-奥曲肽眼眶显像联合MRI诊断活动期的AUC为0.893,高于99Tcm-奥曲肽眼眶显像或MRI单独诊断。结论:对TAO分期诊断中建议联合应用99Tcm-奥曲肽眼眶显像和MRI影像学检查,二者影像学表现典型,且联合应用具有较高诊断效能。AIM:To investigate the efficacy of 99Tcm-octreotide orbital imaging combined with magnetic resonance imaging(MRI)in stage diagnosis of thyroid associated ophthalmopathy(TAO).METHODS:Retrospective analysis of clinical data of 35 surgically treated TAO patients admitted to hospital from June 2017 to June 2018.99Tcm-octreotide orbital imaging and MRI were performed,and the pathological observation and stages were performed.The result of pathological staging was statistically analyzed.The imaging findings and results of 99Tcm-octreotide orbital imaging combined with MRI were observed.The efficacy of 99Tcm-octreotide orbital imaging,MRI,99Tcm-octreotide orbital imaging combined with MRI in the stage diagnosis of TAO was analyzed.RESULTS:Totally 58 eyes with TAO in 35 patients with pathological stages were 49 eyes in the active phases and 9 eyes and inactive phases.99Tcm-octreotide orbital imaging and MRI diagnosis of TAO severity staging have typical imaging findings,and the sensitivity,specificity,accuracy of 99Tcm-octreotide orbital imaging combined with MRI in the diagnosis of active TAO was higher than that of 99Tcm-octreotide orbital imaging and MRI alone.The ROC results showed that the AUC of the active phase of 99Tcm-octreotide orbital imaging combined with MRI diagnosis was 0.893,which was higher than that of 99Tcm-octreotide orbital imaging or MRI alone.CONCLUSION:It is recommended to use 99Tcm-octreotide orbital imaging and MRI imaging in combination with TAO stage diagnosis.The imaging findings are typical,and the combined application has higher diagnostic efficiency.

关 键 词：电子计算机体层扫描 核磁共振成像 甲状腺相关性眼病 分期 

分 类 号：R771.3[医药卫生—眼科] R581[医药卫生—临床医学]