老年人睡眠障碍与认知损害的关系及相关影响因素分析  

Analysis of the relationship between sleep disorder and cognitive impairment in the elderly and its related influencing factors

作　　者：刘小彦 许力新 尚保华 孟苓苓 冯丽梅[1] 张刚[1] 杜义敏[1] 赵刘乐[2] LIU Xiaoyan;XU Lixin;SHANG Baohua;MENG Lingling;FENG Limei;ZHANG Gang;DU Yimin;ZHAO Liule(Second Department of Psychiatry,The Eighth Hospital of Shijiazhuang City,Shijiazhuang,Hebei 050000,China;Department of Traditional Chinese Medicine,The Eighth Hospital of Shijiazhuang City,Shijiazhuang,Hebei 050000,China)

机构地区：[1]石家庄市第八医院精二科,河北石家庄050000 [2]石家庄市第八医院中医科,河北石家庄050000

出　　处：《安徽医药》2021年第4期722-725,共4页Anhui Medical and Pharmaceutical Journal

基　　金：河北省医学科学研究重点课题计划项目(20171002)。

摘　　要：目的探讨老年人认知损害与睡眠障碍的关系并且分析引起认知损害的影响因素,为改善老年人睡眠质量及认知功能提供参考。方法 2016年1月至2017年12月,石家庄市第八医院精二科门诊及病房,通过方便取样对152例伴有失眠的老年人进行问卷调查,并另选取150例健康志愿者(睡眠正常组)进行比较。采用匹茨堡睡眠质量指数量(PSQI)表、蒙特利尔认知评估(MoCA)评分表分别评估老年人的睡眠质量以及认知功能,Spearman相关系数法分析睡眠障碍与认知损害之间的关系,多因素logistic回归分析不同维度睡眠障碍对认知损害的影响。结果 152例睡眠障碍者的PSQI的平均得分为(14.67±1.68)分;其MoCA平均得分(16.79±3.89)分;相关分析结果表明,MoCA总分与各子项均与PSQI总分负相关;多因素logistic回归分析表明,睡眠时间、入睡时间以及日间功能障碍与发生认知损伤差异有统计学意义(P<0.05)。结论睡眠障碍的老年人中认知损害发生率增加,其中合理的睡眠时间、入睡时间可改善认知功能,对认知功能起保护作用;而日间功能障碍与认知损伤相互影响,可导致病情加重。Objective To explore the relationship between cognitive impairment and sleep disorder in the elderly and analyze the influencing factors of cognitive impairment,so as to provide reference for improving sleep quality and cognitive function in the elderly.Methods One hundred and fifty-two seniors with insomnia in the Outpatient and Ward of the Second Department of Spermatology in the Eighth Hospital of Shijiazhuang City from January 2016 to December 2017 were investigated by convenient sampling,and 150 healthy volunteers with normal sleep were selected as normal group.The sleep quality and cognitive function of the elderly were assessed by Pittsburgh Sleep Quality Index(PSQI)and Montreal Cognitive Assessment(MoCA).Spearman correlation coefficient method was used to analyze the relationship between sleep disorders and cognitive impairment.Multivariate logistic regression was used to analyze the effects of different sleep disorders on cognitive impairment.Results The average PSQI score of 152 patients with sleep disorders was(14.67±1.68),and the average MoCA score was(16.79±3.89).The results of correlation analysis showed that the total score of MoCA and its subitems were negatively correlated with the total score of PSQI.Multivariate logistic regression analysis showed that cognitive impairment was statistically different from the length of sleep,time of fall asleep and daytime dysfunction.Conclusions The incidence of cognitive impairment in the elderly with sleep disorders is increasing.Reasonable sleep time and falling asleep time can improve cognitive function and protect cognitive function;while daytime dysfunction and cognitive impairment interact with each other and can lead to illness aggravate.

关 键 词：认知障碍 睡眠障碍 认知损害 相关性 匹茨堡睡眠质量指数量表 蒙特利尔认知评估评分表 老年人 

分 类 号：R740[医药卫生—神经病学与精神病学] R749.1[医药卫生—临床医学]