悬雍垂腭咽成形术患者全麻中的右美托咪定使用方法研究  

Study on the Use of Dexmedetomidine in General Anesthesia for Patients with Uvulapalatopharyngoplasty

作　　者：韩成冰[1] 安世昌[1] 纪凡层[2] 和晓坡[1] HAN Cheng-bing;AN Shi-chang;JI Fan-ceng;HE Xiao-po(Oral and Maxillofacial Surgery,Weifang People's Hospital,Weifang,Shandong Province,261041 China;Department of Anesthesiology,Weifang People's Hospital,Weifang,Shandong Province,261041 China)

机构地区：[1]潍坊市人民医院口腔颌面外科,山东潍坊261041 [2]潍坊市人民医院麻醉科,山东潍坊261041

出　　处：《世界复合医学》2021年第1期20-23,共4页World Journal of Complex Medicine

摘　　要：目的探究悬雍垂腭咽成形术患者全麻中的右美托咪定使用方法。方法从该院2016年12月—2019年12月选取120例进行悬雍垂腭咽成形术的患者,将患者随机分成4组(对照组、观察组1、2、3),每组30例,观察比较不同时间点各组相关指标,苏醒期躁动情况,及术后疼痛情况。结果观察组3无躁动出现,观察组1的1分患者4例(13.33%),观察组2有6例(20.00%),对照组有20例(66.67%),差异有统计学意义(P<0.05);观察组VAS评分明显低于对照组,观察组3最低,拔管后5 min VAS评分观察1组、2组、3组为(3.13±0.01)分、(2.78±0.34)分、(2.46±0.87)分低于对照组为(5.71±0.63)分,差异有统计学意义(P<0.05)。术后24 hVAS评分,观察组1、2、3组为(2.05±1.02)分、(2.01±1.43)分、(1.89±0.96)分低于对照组(3.26±1.47)分,差异有统计学意义(P<0.05)。结论手术结束前30 min,右美托咪定静脉持续泵注15 min1μg/kg,用于悬雍垂腭咽成形术患者全麻质量最高,可以有效减少患者疼痛,缓解苏醒期躁动。Objective To explore the use of dexmedetomidine in general anesthesia for patients undergoing uvulapalatopharyngoplasty.Methods From December 2016 to December 2019,120 patients undergoing uvulopalatopharyngoplasty were selected from the hospital,and the patients were randomly divided into four groups(control group,observation group 1,2,3),30 cases in each group,observed and compare the relevant indicators of each group at different time points,restlessness during recovery period,and postoperative pain.Results No agitation in observation group 3,4 cases(13.33%)in observation group 1,6 cases(20.00%)in observation group 2,and 20 cases(66.67%)in control group,the difference was statistically significant(P<0.05).The VAS of the observation group was significantly lower than that of the control group.The score of observation group 3 was the lowest.5 min after extubation,the VAS score of observation group 1,2 and 3 were(3.13±0.01)points,(2.78±0.34)points,(2.46±0.87)points lower than the control group(5.71±0.63)points,the difference was statistically significant(P<0.05).VAS scores at 24 h after operation were(2.05±1.02)points,(2.01±1.43)points,(1.89±0.96)points in the observation group 1,2,and 3,which were lower than the control group(3.26±1.47)points,the difference was statistically significant(P<0.05).Conclusion 30 min before the end of the operation,dexmedetomidine was injected intravenously at 1μg/kg for 15 min.The quality of general anesthesia for patients undergoing uvulopalatopharyngoplasty is the highest,which can effectively reduce pain and relieve agitation during the recovery period.

关 键 词：悬雍垂腭咽成形术 全麻 右美托咪定 躁动 疼痛 

分 类 号：R782.054[医药卫生—口腔医学]