从“汁沫与血相抟”论线粒体功能障碍与动脉粥样硬化  

Discussion on Mitochondrial Dysfunction and Atherosclerosis from"Body Fluids and Blood Mingled"

作　　者：杨平[1,2] 宋囡[3] 贾连群[3] 杨关林[3] YANG Ping;SONG Nan;JIA Lianqun;YANG Guanlin(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China;Key Laboratory of Ministry of Education for Traditional Chinese Medicine Viscera-State Theory and Applications of Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China)

机构地区：[1]辽宁中医药大学,辽宁沈阳110847 [2]辽宁中医药大学附属医院,辽宁沈阳110032 [3]辽宁中医药大学中医脏象理论及应用教育部重点实验室,辽宁沈阳110847

出　　处：《中华中医药学刊》2021年第2期95-98,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金(81974548);辽宁省中央引导地方科技发展专项(2017105002);沈阳市科技计划(17-139-8-00)。

摘　　要："汁沫与血相抟"始见于《黄帝内经》,是对痰瘀互结致病的高度总结,中医认为脾虚所导致的痰瘀互结是引发动脉粥样硬化的重要因素。现代医学认为线粒体功能障碍是诱发动脉粥样硬化重要机制。因此基于"脾-线粒体"相关性,从"汁沫与血相抟"论证探讨动脉粥样硬化发病机制,为中西医结合防治动脉粥样硬化提供新理论与新策略。"Body fluids and blood mingled"was early mentioned in Neijing.It is the early understanding and highly summary of phlegm and blood stasis.Traditional Chinese medicine considers the phlegm and blood stasis caused by spleen deficiency is an important factor in the development of atherosclerosis.Modern medicine believes that mitochondrial dysfunction is an important mechanism that induces atherosclerosis.Therefore,with the theory of"spleen-mitochondria",the discussion on"body fluids and blood mingled"has a connection with atherosclerosis.It provides a new theory and strategy for the prevention and treatment of atherosclerosis with the combination of traditional Chinese and western medicine.

关 键 词：汁沫与血相抟 脾虚 线粒体功能障碍 动脉粥样硬化 

分 类 号：R259.431.2[医药卫生—中西医结合]