子宫内膜癌合并子宫肌瘤疾病的临床病理分析  

Clinicopathological analysis of endometrial carcinoma with uterine fibroids

作　　者：李翠[1] 钱慧珍[1] 李聪[1] 杨美娇[1] 李佳超 LI Cui;QIAN Hai-zhen;LI Cong(Department of Pathology,Shengjing Hospital Dalian Hospital Affiliated to China Medical University,Dalian 116000,China)

机构地区：[1]中国医科大学附属盛京医院大连医院病理科,116000

出　　处：《中国实用医药》2021年第7期32-34,共3页China Practical Medicine

摘　　要：目的探析子宫内膜癌并发子宫肌瘤疾病的临床病理特征。方法回顾性分析50例子宫内膜癌患者的临床资料,其中单发子宫内膜癌患者26例(乙组),子宫内膜癌并发子宫肌瘤患者24例(甲组)。比较两组手术病理分期、肿瘤病理组织分级、肌层浸润度情况及雌、孕激素阳性检出率。结果甲组手术病理分期明显优于乙组,差异具有统计学意义(P<0.05)。甲组肿瘤病理组织分级明显优于乙组,差异具有统计学意义(P<0.05)。甲组肌层浸润度<1/2患者20例(83.33%),≥1/2患者4例(16.67%);乙组肌层浸润度<1/2患者14例(53.85%),≥1/2患者12例(46.15%);甲组肌层浸润度显著优于乙组,差异具有统计学意义(P<0.05)。甲组雌、孕激素阳性检出例数分别为19例(79.17%)、22例(91.67%),乙组雌、孕激素阳性检出例数分别为9例(34.62%)、15例(57.69%);甲组雌、孕激素阳性检出率均明显高于乙组,差异具统计学意义(P<0.05)。结论子宫内膜癌并发子宫肌瘤疾病多为雌激素肿瘤,且具有较高的依赖度,与单一子宫内膜癌相比,子宫内膜癌肌层浸润度更浅、高危影响因素更少,总体预后良好。Objective To discuss and analyze the clinicopathological features of endometrial carcinoma with uterine fibroids. Methods The clinical data of 50 patients with endometrial carcinoma were retrospectively analyzed, including 26 patients with endometrial carcinoma(group B) and 24 patients with endometrial carcinoma complicated with uterine fibroids(group A). The surgical pathological staging, tumor pathological tissue classification, myometrial invasion, and the positive detection rate of estrogen and progesterone were compared between the two groups. Results The surgical pathological staging of group A was obviously better than that of group B, and the difference was statistically significant(P<0.05). The tumor pathological tissue classification of group A was obviously better than that of group B, and the difference was statistically significant(P<0.05). In group A, 20 cases(83.33%) had myometrial invasion <1/2 and 4 cases(16.67%) had myometrial invasion ≥1/2;in group B, there were 14 cases(53.85%) with muscle invasion <1/2 and 12 cases(46.15%) with muscle invasion ≥1/2. The myometrial invasion of group A was significantly better than that of group B, and the difference was statistically significant(P<0.05). The number of positive estrogen and progesterone detection in group A were 19 cases(79.17%) and 22 cases(91.67%), and the number of positive estrogen and progesterone detections in group B were 9 cases(34.62%) and 15 cases(57.69%). The positive detection rate of estrogen and progesterone in group A was significantly higher than that in group B, and the difference was statistically significant(P<0.05). Conclusion Endometrial cancer complicated by uterine fibroids are mostly estrogen tumors and have a high degree of dependence. Compared with endometrial cancer, endometrial cancer has a shallower myometrial invasion and fewer high-risk factors, and the prognosis is good.

关 键 词：子宫内膜癌 子宫肌瘤 浸润程度 效果 

分 类 号：R737.33[医药卫生—肿瘤]