全飞秒小切口透镜取出术与飞秒激光置瓣LASIK术治疗屈光不正患者的效果比较  

Effects of full femtosecond small incision lens extraction and femtosecond laser flap LASIK in patients with ametropia

作　　者：张蕊[1] 张巧思 梁巍[1] 于春晶[1] ZHANG Rui;ZHANG Qiao-si;LIANG-Wei;YU Chun-jing(Department of Ophthalmology,Dalian Third People′s Hospital,Liaoning Province,Dalian116033,China)

机构地区：[1]大连市第三人民医院眼科,辽宁大连116033

出　　处：《中国当代医药》2021年第9期68-71,共4页China Modern Medicine

摘　　要：目的探讨全飞秒小切口透镜取出术与飞秒激光置瓣激光原位角膜磨镶(LASIK)术治疗屈光不正患者的临床效果。方法选取2018年5月~2019年5月大连市第三人民医院收治的屈光不正预行手术矫正患者80例(160眼)为研究对象,按照随机数字表法分为观察组(40例)和对照组(40例)。观察组行全飞秒小切口透镜取出(SMILE)术,对照组行LASIK术,随访1年,比较两组手术前后角膜内皮细胞密度、角膜知觉眼表疾病指数(OSDI)评分、眼压及视力变化、并发症发生情况。结果术后1年,观察组角膜内皮细胞密度大于对照组,差异有统计学意义(P<0.05),观察组角膜知觉OSDI评分高于术后对照组,差异有统计学意义(P<0.05),术后及术后1年观察组眼压低于对照组,视力水平高于对照组,差异有统计学意义(P<0.05),观察组术后并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论全飞秒SMILE手术能有效的促进术后角膜功能恢复,改善视力,并发症少,安全性高。Objective To investigate the clinical effect of femtosecond small incision lens removal and femtosecond laser in situ keratomileusis(LASIK)in the treatment of patients with ametropia.Methods A total of 80 patients(160 eyes)with ametropia who underwent preoperative correction in the Third People′s Hospital of Dalian from May 2018 to May 2019 were selected as the research subjects.According to random number table method,they were divided into observation group(40 cases)and control group(40 cases).The observation group received full femtosecond small incision lens removal(SMILE)surgery,and the control group received LASIK surgery.The follow-up period was 1 year.The corneal endothelial cell density,corneal perceptual ocular surface disease index(OSDI)score,intraocular pressure and visual acuity changes,and the incidence of complications were compared between the two groups before and after surgery.Results One year after operation,the density of corneal endothelial cells in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).The OSDI score of the observation group was higher than that of the postoperative control group,the difference was statistically significant(P<0.05).The intraocular pressure of the observation group was lower than that of the control group,and the visual acuity of the observation group was higher than that of the control group after the operation and one year after the operation,the differences were statistically significant(P<0.05).The incidence of postoperative complications in the observation group was lower than that in the control group,with statistical significance(P<0.05).Conclusion Full femtosecond SMILE surgery can effectively promote the recovery of corneal function and improve visual acuity,with fewer complications and high safety.

关 键 词：全飞秒小切口透镜取出术 飞秒激光置瓣激光原位角膜磨镶术 角膜内皮细胞密度 角膜知觉眼表疾病指数评分 视力 眼压 并发症 

分 类 号：R778[医药卫生—眼科]