中国1076名儿童及青年腭中缝影像学分期与其颈椎骨龄分期的相关性研究  

Correlation between midpalatal suture stage on cone-beam CT images and its cervical vertebral maturation stage for 1076 Chinese children and youth

作　　者：高璐 谷岩[1] Gao Lu;Gu Yan(Department of Orthodontics,Peking University School and Hospital of Stomatology&National Clinical Research Center for Oral Diseases&National Engineering Laboratory for Digital and Material Technology of Stomatology&Beijing Key Laboratory of Digital Stomatology,Beijing 100081,China)

机构地区：[1]北京大学口腔医学院·口腔医院正畸科,国家口腔疾病临床医学研究中心,口腔数字化医疗技术和材料国家工程实验室,口腔数字医学北京市重点实验室,100081

出　　处：《中华口腔医学杂志》2021年第3期251-255,共5页Chinese Journal of Stomatology

基　　金：国家自然科学基金(81970979);科技部科技基础资源调查专项课题(2018FY101005)。

摘　　要：目的通过锥形束CT研究中国儿童及青年腭中缝分期(midpalatal suture stage,MPS)与颈椎骨龄分期(cervical vertebral maturation stage,CS)的相关性,探讨CS对腭中缝骨化闭合程度的预测能力。方法回顾性收集2013年1月至2018年4月于北京大学口腔医学院·口腔医院医学影像科拍摄锥形束CT的1076名≥6岁且<21.0岁的骨性Ⅰ类错儿童及青年锥形束CT资料,其中男性401名,女性675名,观察锥形束CT轴位腭中缝区域,记录MPS与CS。MPS共分5期,包括1、2、3、4s1(亚期)、4s2(亚期)、5期;CS共分6期,包括1~6期。采用Spearman相关系数检验与诊断试验的方法,研究有序分类变量MPS与CS的相关关系。结果CS与MPS的Spearman相关系数为0.803。诊断效能从强到弱的CS与MPS配对依次为CS 6期与MPS 5期、CS 5期与MPS 4s2期、CS 1期与MPS 1期、CS 4期与MPS 4s1期、CS 2期与MPS 1期、CS 3期与MPS 3期。CS 1~3期者90.9%(309/340)处于MPS 1~3期,另9.1%(31/340)处于MPS 4s1期。CS 4期者33.0%(107/324)处于MPS 3期,46.6%(151/324)处于MPS 4s1期。结论CS与中国儿童及青年MPS相关性较强。处于CS 4期、拟采用传统牙支持式上颌快速扩弓患者有必要于矫治前拍摄锥形束CT,以明确腭中缝骨化闭合状态。Objective To investigate the correlation between cone-beam CT(CBCT)morphological stage of midpalatal suture(MPS)and cervical vertebral maturation stage(CS)of Chinese children and youth.Methods This study was a retrospective observational study.A total of 1076 CBCT images(male:401,female:675,age≥6.0 years old and<21.0 years old)taken from January 2013 to April 2018 in Peking University School and Hospital of Stomatology were included.MPS and CS of each sample were recorded according to previous studies.MPS included five stages:MPS 1,MPS 2,MPS 3,MPS 4s1(substage),MPS 4s2(substage),and MPS 5.CS included six stages:CS 1-6.Correlation between MPS and CS(ordinal categorical variables)was investigated by Spearman correlation coefficient and diagnostic test analysis.Results Spearman coefficient between CS and MPS was 0.803.Diagnostic pairs with the best diagnostic performance include:CS 6-MPS 5,CS 5-MPS 4s2,CS 1-MPS 1,CS 4-MPS 4s1,CS 2-MPS 1,CS 3-MPS 3.The 90.9%(309/340)of individuals at CS 1-3 were at MPS 1-3 and 9.1%(31/340)were at MPS 4s1.The 33.0%(107/324)of individuals at CS 4 were at MPS 3 and 46.6%(151/324)were at MPS 4s1.Conclusions CS has a close relationship with MPS.Individuals at CS 4 are recommended to take pre-treatment CBCT,so as to estimate feasibility of skeletal expansion with traditional tooth-borne rapid maxillary expansion.

关 键 词：生长和发育 锥束计算机体层摄影术 腭中缝 颈椎骨龄分期 

分 类 号：R783.5[医药卫生—口腔医学]