海绵状淋巴管瘤八例临床分析  

Clinical analysis of 8 cases of cavernous lymphangioma

作　　者：韩欣欣[1] 沙悦[1] 曾学军[1] Han Xinxin;Sha Yue;Zeng Xuejun(Department of General Internal Medicine,Peking Union Medical College Hospital,Chinese Academy of Medical Science&Peking Union Medical College,Beijing 100730,China)

机构地区：[1]中国医学科学院,北京协和医学院,北京协和医院全科医学科(普通内科),100730

出　　处：《中华全科医师杂志》2021年第3期349-352,共4页Chinese Journal of General Practitioners

摘　　要：目的探讨海绵状淋巴管瘤的临床特征、治疗及预后。方法回顾性分析1990年1月至2020年7月北京协和医院住院诊治的8例经病理检查诊断的海绵状淋巴管瘤患者的临床资料,包括临床表现、实验室与影像学检查结果及治疗方案。结果8例海绵状淋巴管瘤患者均为女性,发病年龄1日龄~58岁,中位年龄32岁,病程24(5,78)个月。临床表现为腹部肿物2例,腋下肿物2例,颈部肿物1例,腹股沟肿物1例,下颌肿物1例,胸腔与腹腔积液1例。8例中,1例为出生后起病,其余均为成人后起病。2例患者起病前有邻近部位的手术史。5例患者行CT扫描检查示肿物为低密度、类圆形肿物,增强后无明显强化。7例患者行肿物完整切除术;1例患者曾行肿物部分切除术,术后服中链脂肪酸饮食治疗。4例随访3.5(1.3~17.8)年均稳定,2例在术后13、1年后复发,1例患者随访中诊断为鲍温病。结论海绵状淋巴管瘤可先天出现也可后天产生,以女性受累为主,常见的临床表现为体表肿物,可行手术切除治疗,但易复发,需长期随诊。Objective To analyze the clinical features,treatment efficacy and prognosis of cavernous lymphangioma.Methods The clinical manifestations,laboratory findings,imaging examinations and treatment of 8 patients with pathology-diagnosed cavernous lymphangioma admitted in Peking Union Medical College Hospital from January 1990 to July 2020 were retrospectively analyzed.Results All the patients were female.The onset age ranged from 0 to 58 years,with a course of 24(5,78)months.There were 2 cases of abdominal mass,2 cases of axillary mass,1 case of neck mass,1 case of inguinal mass,1 case of mandibular mass and 1 case of pleural and peritoneal effusion.Seven cases had adult onset and 1 case had congenital onset.Two patients had had history of surgery adjacent to lesion sites.Contrast-enhanced CT scan showed a low-density round mass with no significant enhancement in 5 patients.Seven patients underwent complete resection of the mass,1 patient received partial resection and intervention with medium-chain fatty-acid diet.During the follow-up,4 patients were stable after 3.5(1.3-17.8)years,while 2 patients relapsed 1 and 13 year after surgery,respectively.Additionally,one patient was diagnosed with Bowen disease.Conclusion Cavernous lymphangioma can be congenital or acquired and usually occurs in female.The body mass is the common clinical manifestation;and surgery is the most common treatment,but it is prone to relapse and requires long-term follow-up.

关 键 词：淋巴管瘤 海绵状淋巴管瘤 体征和症状 淋巴结切除术 治疗结果 

分 类 号：R733.1[医药卫生—肿瘤]