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作 者:王永花[1] 张宽[1] WANG Yonghua;ZHANG Kuan(Department of Radiation Oncology,Qinghai Red Cross Hospital,Xining 810000,China)
出 处:《医学综述》2021年第7期1340-1344,共5页Medical Recapitulate
摘 要:随着外科手术及放化疗技术的不断发展,早期宫颈癌患者的远期疗效显著提高,生存时间得以延长,但中晚期宫颈癌患者因病情较重,术后仍存在较高的复发风险。宫颈癌患者在接受外科手术后一旦复发,部分有条件者可行二次手术治疗,但多数患者无再次手术指征,需要接受放化疗等辅助治疗方案,患者获益较差,生存状况不理想。因此,明确宫颈癌术后复发的影响因素尤为重要。影响宫颈癌患者术后复发的因素较多,包括手术方式、间质浸润深度、肿瘤大小、组织分化程度等,但由于受较多因素影响,目前尚未达成统一意见,同时还有其他可能的影响因素尚待证实,具体结论还需未来深入研究进行讨论、验证。With the continuous development of surgery,radiotherapy and chemotherapy technology,the long-term efficacy of patients with early cervical cancer has been significantly improved,and the survival time has been prolonged,but due to the severe condition of disease in patients with advanced cervical cancer,there is still a higher risk of postoperative recurrence.Once cervical cancer recurs after surgery,some patients with certain condition can receive surgical treatment for the second time,some patients can be treated by second surgery,but most patients have no indication of reoperation,and need to receive adjuvant therapy such as radiotherapy and chemotherapy,often with poor benefit and poor survival.Therefore,it is important to identify the influencing factors of postoperative recurrence of cervical cancer,which includes a variety,such as operation mode,depth of interstitial infiltration,tumor size,tissue differentiation degree,etc.,where a consensus has not yet been reached.There are other possible factors to be confirmed,and the specific conclusions need to be further discussed and verified in the future.
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