Evidence-Based Immunotherapeutic Effects of Herbal Compounds on Humoral Immunity:Ancient and New Approaches  

作　　者：Fatemeh Nejatbakhsh Mohammad Ali Zareian Mahdi Yaseliani Hassan Abolhassani 

机构地区：[1]Department of Iranian Traditional Medicine,School of Traditional Medicine,Tehran University of Medical Sciences,Tehran(14166),Iran [2]Research Center for Immunodeficiencies,Pediatrics Center of Excellence,Children's Medical Center,Tehran University of Medical Sciences,Tehran(14194),Iran [3]Division of Clinical Immunology,Department of Laboratory Medicine,Karolinska Institute,Karolinska University Hospital Huddinge,Stockholm(SE-14186),Sweden

出　　处：《Chinese Journal of Integrative Medicine》2021年第4期313-320,共8页中国结合医学杂志（英文版）

摘　　要：The human immune system represents a dynamic multiscale system with high complexity in biology.Humoral immunity,as the main branch of adaptive immunity,is characterized by differentiated stages of the Blymphocytes,producing the final product of antibodies that has a diversity of the tuning mechanisms within genetic and epigenetic levels in confrontation with environmental exposures.Disorders because of disturbed humoral immunity are linked with dysregulation of feedback-regulated signaling and the dynamic of immune components that determine the overall response.Food products,mainly herbal components have a significant role in tailoring the immune system micro-ecosystem which can diversify the adaptive nature of humoral immunity.Herein,we review the current evidence-based approaches for the impact of medicinal herbs on humoral immunity signaling and antibody production with a focus on immunotherapeutic applications.

关 键 词：Bcells adaptive immunity ANTIBODY IMMUNOTHERAPY medicinal herb 

分 类 号：R285[医药卫生—中药学]