牙龈卟啉单胞菌与不良妊娠结局的相关研究进展  

Progress of research on correlations between Porphyromonas gingivalis and adverse pregnancy outcomes

作　　者：齐帅 林晓萍[1] QI Shuai;LIN Xiaoping(Department of Stomatology,Shengjing Hospital of China Medical University,Shenyang 110004,China)

机构地区：[1]中国医科大学附属盛京医院口腔综合门诊,辽宁沈阳110004

出　　处：《口腔医学》2021年第3期265-268,共4页Stomatology

基　　金：国家自然科学基金(81570988);中华口腔医学会专项基金研究项目(CSA-Z2015-07)。

摘　　要：牙龈卟啉单胞菌(Porphyromonas gingivalis,P.gingivalis)是一种革兰阴性厌氧菌,是牙周炎尤其是慢性牙周炎病变区或活动部位最主要的病原菌。研究表明,牙周炎与多种不良妊娠结局(adverse pregnancy outcomes,APO)有关,这一过程涉及多种病理生理机制,而P.gingivalis作为关键牙周致病菌之一在其中扮演重要角色。目前我们对P.gingivalis与APO的关系及其作用机制的认识仍然十分有限。该文拟通过回顾近年来发现的P.gingivalis与APO之间相关的直接或间接的证据,对P.gingivalis与APO的联系和作用机制作一综述。Porphyromonas gingivalis(P.gingivalis)is a gram-negative anaerobic bacterium,which is the main pathogen of periodontitis,especially chronic periodontitis.Studies have shown that periodontitis is related to adverse pregnancy outcomes(APO).This process involves a variety of pathophysiological mechanisms,and P.gingivalis,as one of the key periodontal pathogens,plays an important role in the process.At present,our understanding of the relationship between P.gingivalis and APO and its mechanism of interaction is still limited.This paper intends to review the direct or indirect evidence of the relationship between P.gingivalis and APO in recent years,and to make a review of the relationship and mechanism of interaction between P.gingivalis and APO.

关 键 词：牙周炎 牙周致病菌 牙龈卟啉单胞菌 不良妊娠结局 

分 类 号：R781.42[医药卫生—口腔医学]