TAPP1 Represses the Differentiation of Oligodendrocyte and its Deficiency Accelerates Myelin Regeneration after Demyelinating Injuries  

作　　者：Ruyi Mei Jiaying Fu Chunxia Jiang Junlin Yang Kang Zheng Aifen Yang Mengsheng Qiu Xiaofeng Zhao 

机构地区：[1]Institute of Developmental and Regenerative Biology,Zhejiang Key Laboratory of Organ Development and Regeneration,College of Life and Environmental Sciences,Hangzhou Normal University,Hangzhou 310036,China [2]The College of Life Sciences,Zhejiang University,Hangzhou 310058,China

出　　处：《Neuroscience Bulletin》2021年第3期385-388,共4页神经科学通报（英文版）

基　　金：supported by the Natural Science Foundation of Zhejiang Province,China(LY17C090006,LQ16C090004,and LY18H090014)。

摘　　要：Dear Editor,Myelin,the lipid-rich insulation that supports the integrity of axons,enables rapid conduction of nerve impulses and information flow to distant brain areas[1].Oligodendrocytes(OLs)are glial cells that myelinate axons with specialized lipid membrane extensions[2].OL progenitor cells(OPCs)arise from neural stem cells[3],and undergo proliferation before terminal differentiation and eventual myelination.Impairment at any stage of OL development can affect myelin formation.

关 键 词：insulation conduction enable 

分 类 号：R744.5[医药卫生—神经病学与精神病学]