中西医结合治疗帕金森共病抑郁34例临床观察  

Clinical Observation on 34 Cases of Depression Caused by Parkinson's Comorbidity Treated with Combination of Traditional Chinese and Western Medicine

作　　者：王磊 安永辉[2] WANG Lei;AN Yonghui(Department of Internal Medicine of Traditional Chinese and Western Medicine,Henan Provincial Construction Hospital,Zhengzhou 45000,China;Department of Traditional Chinese and Western Medicine Infection,Zhengzhou Sixth People’s Hospital,Zhengzhou 45000,China)

机构地区：[1]河南省建筑医院中西医结合内科,河南郑州450000 [2]郑州市第六人民医院中西医结合感染科,河南郑州450000

出　　处：《中国民族民间医药》2021年第6期106-109,共4页Chinese Journal of Ethnomedicine and Ethnopharmacy

摘　　要：目的:观察中西医结合治疗帕金森病共病抑郁的临床疗效。方法:选取帕金森病共病抑郁对象68例,按就诊顺序,采用单双号法将其分为对照组和观察组各34例。比较治疗前后两组帕金森病症状、抑郁症状、用药期间不良事件发生率及治疗结束后随访半年的生存质量。结果:随访半年相比治疗前,两组躯体功能、心理功能、社会功能、物质生活状态及总体生活质量评分均升高,且随访半年对照组躯体功能、心理功能、社会功能、物质生活状态及总体生活质量评分均低于观察组(P<0.05);治疗4周、8周,对照组药物副反应量表(TESS)评分高于观察组(P<0.05);对照组帕金森病共病抑郁治疗总有效率均低于观察组(P<0.05)。结论:中西医结合治疗帕金森病共病抑郁收效较好。Objective To observe the effect of integrated traditional Chinese and western medicine in the treatment of Parkinson's disease comorbid depression.Methods Select 68 patients with Parkinson's disease comorbid depression.According to the order of treatment,the included objects were divided into a control group and an observation group(34 cases in each)by the odd and even number method.The incidence of Parkinson's disease symptoms,depressive symptoms,adverse events during medication and the quality of life of the included subjects before and after treatment were compared.Results Follow-up for six months compared to before treatment,the scores of physical function,psychological function,social function,material life status and overall quality of life of the two groups were increased,and the scores of physical function,psychological function,social function,material life status and overall quality of life of the control group were lower than those of the observation group(P<0.05).After 4 weeks and 8 weeks of treatment,the TESS score of the control group was higher than that of the observation group(P<0.05).The total effective rate of Parkinson's disease comorbid depression treatment in the control group was lower than that in the observation group(P<0.05).Conclusion The combination of traditional Chinese and Western medicine in the treatment of depression of Parkinson's disease comorbidity is effective.

关 键 词：帕金森病 抑郁 中西医结合 

分 类 号：R742.5[医药卫生—神经病学与精神病学]