Good’s综合征合并支气管扩张1例并文献复习  

Good’s syndrome combined with bronchiectasis:A case report and literature review

作　　者：任思颖[1] 胡衍[1] 肖迎 纵单单[1] 彭雅婷[1] 刘青清[1] 贾玉楠 欧阳若芸[1] REN Siying;HU Yan;XIAO Ying;ZONG Dandan;PENG Yating;LIU Qingqing;JIAYunan;OUYANG Ruoyun(Department of Respiratory Diseases,Second Xiangya Hospital,Central South University,Changsha 410011,China)

机构地区：[1]中南大学湘雅二医院呼吸内科,长沙410011

出　　处：《中南大学学报（医学版）》2021年第3期328-332,共5页Journal of Central South University ：Medical Science

基　　金：国家临床重点专科建设项目(2012-650);国家自然科学基金(81700070);国家重点研发计划(2016YFC0901502);湖南省自然科学基金(2019JJ30038);湖南省卫生计生委科研项目(B2018-0541)。

摘　　要：回顾性分析1例胸腺瘤相关免疫缺陷综合征(Good’s综合征)合并支气管扩张病例,结合最新文献从发病机制分析Good’s综合征患者的常见临床症状、实验室检查结果及治疗策略。因支气管扩张、反复感染就诊时,应警惕其免疫状态,详细了解病史。若当患者有胸腺瘤病史应考虑Good’s综合征作为鉴别诊断。Good’s综合征患者极易出现致死性机会感染,当考虑为Good’s综合征时,应及时给予丙种球蛋白等免疫支持治疗,避免和预防感染。早期免疫状态筛查和积极纠正原发免疫缺陷对于Good’s综合征患者的诊断和预后很有价值。A patient with thymoma associated immunodeficiency syndrome(Good’s syndrome)and bronchiectasis was retrospectively analyzed.Good’s syndrome is a rare condition of immunodeficiency that is characterized by thymoma and hypogammaglobulinemia.It is important to bear in mind that Good’s syndrome should be included in the differential diagnosis When patients repeatedly visited for bronchiectasis or infection,we should alert to their immune state and history of thymoma.Early screening of immunological status and aggressive correction of immune deficiency are beneficial to improving the prognosis to patients with Good’s syndrome.

关 键 词：胸腺瘤 胸腺瘤相关免疫缺陷综合征 支气管扩张 

分 类 号：R736.3[医药卫生—肿瘤] R562.22[医药卫生—临床医学]