前哨淋巴结活检在子宫恶性肿瘤中应用的研究进展  

Research Progress of Sentinel Lymph Node Biopsy in Uterine Cancer

作　　者：尹俊杨 叶元[1] Yin Junyang;Ye Yuan(Department of 0bstetrics and Cynecology,Affiliated Hospital of Guilin Medical University,Guilin 541001,Guangxi,China)

机构地区：[1]桂林医学院附属医院妇产科,广西桂林541001

出　　处：《肿瘤预防与治疗》2021年第3期269-273,共5页Journal of Cancer Control And Treatment

基　　金：2016年广西重点研发计划项目(编号:AB17292085)。

摘　　要：子宫恶性肿瘤以宫颈癌和子宫内膜癌最为常见,患者的淋巴结转移状态与其预后密切相关.早期患者发生淋巴结转移的风险低.传统的根治术在切除盆腔淋巴结后会导致诸多并发症的出现,严重影响患者术后生活质量.前哨淋巴结活检术的应用,在明确区域淋巴结肿瘤转移状态的同时也避免了淋巴结阴性的患者接受不必要的系统淋巴结切除术.在提高前哨淋巴结活检的检出率、灵敏度、阴性预测值及降低假阴性率方面,联合示踪剂较单一示踪剂更具应用前景,并且病理超分期检测的应用,使得肿瘤发生淋巴结微转移的检出率大幅度提升.现本文就前哨淋巴结活检术在早期子宫恶性肿瘤中的应用进展进行综述.Cervical cancer and endometrial cancer are the most common uterine malignancies. Lymph node metastasis is closely related to the prognosis of patients. There is a low risk of lymph node metastasis in early stage patients. Traditional radical surgery tends to cause many complications that seriously affects the quality of life of patients. Sentinel lymph node biopsy determines the status of regional lymph node metastasis without unnecessary systemic lymph node dissection in patients with negative lymph nodes. Combined tracer is a more promising than single tracer in improving the detection rate, sensitivity and negative predictive value, and in reducing false negative rate of sentinel lymph node biopsy. And the application of pathological ultrastaging greatly improves the detection rate of lymph node micro-metastasis of tumor. This article reviews the progress of sentinel lymph node biopsy in early uterine malignant tumors.

关 键 词：宫颈癌 子宫内膜癌 前哨淋巴结活检 示踪剂 病理超分期 

分 类 号：R737.33[医药卫生—肿瘤] R730.4[医药卫生—临床医学]