复方薄荷脑-硼酸氧化锌散的真空微波干燥工艺筛选  

Optimize the Vacuum Microwave Drying Process for Compound Menthol-zinc Oxide Borate Powder

作　　者：符宋锋 吴军军 叶树兰 FU Song-feng;WU Jun-jun;YE Shu-lan(Pharmacy department,Hospital of Traditional Chinese medicine in Ningde,Ningde 352000,China;manufacturing laboratory,Hospital of Traditional Chinese medicine in Ningde,Ningde 352000,China)

机构地区：[1]宁德市中医院药剂科,福建宁德352000 [2]宁德市中医院制剂室,福建宁德352000

出　　处：《海峡药学》2021年第3期7-11,共5页Strait Pharmaceutical Journal

摘　　要：目的筛选复方薄荷脑-硼酸氧化锌散的最佳真空微波干燥工艺。方法采用L 18(36)正交实验,以复方薄荷脑-硼酸氧化锌散的干燥失重、薄荷脑含量为量化考察指标,优选最佳干燥工艺。结果优选的最佳真空微波干燥工艺为,干燥温度40℃,真空度0.7 MPa,干燥时间30 min,升温速度1℃/min,每盘物料平辅厚度约4 cm(即每盘物料装量约2 kg)。结论优选的最佳真空微波干燥工艺适用于复方薄荷脑-硼酸氧化锌散的干燥工序。OBJECTIVE To optimize the best vacuum microwave drying process of compound menthol-zinc oxide borate powder.METHODS Optimizing the best drying process according to quantitative inspection indexes of menthol content and dying loss of compound menthol-zinc oxide borate powder,adopt by orthogonal experiment L 18(36).RESULTS The best vacuum microwave drying process stand for the dry temperature was 40℃,the vacuum degree was 0.7 MPa,the drying time was 30 min,the rate of temperature increase was 1℃/min and the flat auxiliary thickness was 4 cm nearly each plate(2 kg load per plate similarly).CONCLUSION The best vacuum microwave drying process had optimized suit for dying of compound menthol-zinc oxide borate powder.

关 键 词：复方薄荷脑-硼酸氧化锌散 真空微波干燥 工艺筛选 正交实验 

分 类 号：R94[医药卫生—药剂学]