脑干梗死患者的面神经F波研究  

Study of facial nerve F wave in patients with brainstem infarction

作　　者：王春雷 朵慧敏[2] 石秋环 杨春晓[2] 侯友文 WANG Chunlei;DUO Huimin;SHI Qiuhuan(Department of Neurology,Harbin Second Hospital Heilongjiang Harbin 150036,China)

机构地区：[1]哈尔滨市第二医院神经内科,黑龙江哈尔滨150036 [2]哈尔滨医科大学附属第二医院神经内科,黑龙江哈尔滨150001

出　　处：《中风与神经疾病杂志》2021年第3期245-248,共4页Journal of Apoplexy and Nervous Diseases

基　　金：黑龙江省卫生健康委科研项目(No.2018152)。

摘　　要：目的研究脑干梗死患者的面神经F波的动态变化,探讨其对脑干梗死急性期的诊断及预后评估的价值。方法纳入我院脑干梗死患者53例,分别于发病3 d、7 d、14 d、1 m、3 m给予电生理检查,包括面神经F波出现率、潜伏期,并与健侧做对比。发病3 m时根据mRS神经功能评分分为预后良好组(mRS评分≤2分)和预后不良组(mRS评分>2分),同时纳入10例健康成年人作对照组,检测方法相同。对比不同时间点面神经F波出现率和潜伏期。结果53例脑干梗死患者分别于发病3 d、7 d、14 d均出现了F波的出现率下降和潜伏期延长,与健侧比较差异有统计学意义(P<0.05);但发病3 m时潜伏期有所恢复,与健侧比较差异不具有统计学意义(P>0.05),而出现率与健侧比较差异仍有统计学意义(P<0.05);不同类型脑干梗死患者分组后发现3 d、7 d各组之间F波出现率和潜伏期都出现了不同程度的下降,差异不具有统计学意义(P>0.05);Raymond-Cestan综合征组于14 d开始F波出现率和潜伏期率先恢复,与其他各组比较差异有统计学意义(P<0.05);Millard-Gubber综合征组于发病1 m、3 m时F波出现率和潜伏期均重于其他组,差异有统计学意义(P<0.05);进行预后分组后发现发病3 d、7 d两组F波潜伏期和出现率增下降,差异不具有统计学意义(P>0.05),14 d开始,预后良好组潜伏期和F波出现率先于预后不良组恢复,差异有统计学意义(P<0.05);于发病3 m时,预后良好组F波出现率明显高于预后不良组,差异有统计学意义;而潜伏期两组都有明显的恢复,差异无统计学意义(P>0.05)。结论脑干梗死患者早期即可出现面神经F波和潜伏期的改变,但急性期对不同类型的脑梗死无鉴别诊断价值,急性期过后可预后评估提供有价值的客观依据。Objective To study the dynamic changes of facial nerve F wave in patients with brainstem infarction,and to explore its value in diagnosis and prognosis evaluation of acute brainstem infarction.Methods Fifty-three patients with brainstem infarction were enrolled in our hospital.Electrophysiological examinations were performed on the 3rd,7th,14th,1st and 3rd days of onset,including the occurrence rate and latency of facial nerve F wave,and compared with the healthy side.Three months after onset,the patients were divided into good prognosis group(mRS≤2)and poor prognosis group(mRS>2)according to mRS neurological function score,and 10 healthy adults were included as control group with the same detection method.The incidence and latency of facial nerve F wave at different time points were compared.Results 53 patients with brainstem infarction showed a decrease in the occurrence rate of f wave and an extension in the latency period on the 3rd,7th and 14th days of onset respectively,with a statistically significant difference compared with the healthy side(P<0.05).However,the incubation period recovered at 3 months after onset,with no significant difference compared with the healthy side(P>0.05),while the occurrence rate was still statistically significant compared with the healthy side(P<0.05).In patients with different types of brainstem infarction,the occurrence rate and incubation period of f wave in each group decreased to different degrees on the 3rd and 7th day,and the difference was not statistically significant(P>0.05).The occurrence rate and incubation period of f wave in Raymond-Cestan syndrome group first recovered from the 14th day,with significant difference compared with other groups(P<0.05).The occurrence rate and incubation period of f wave in Millard-Gubber syndrome group were higher than those in other groups at the 1st and 3rd month of onset,the difference was statistically significant(P<0.05).On the 3rd and 7th day of onset,the incubation period and occurrence rate of f wave in the two groups incr

关 键 词：脑干梗死 面神经F波 出现率 潜伏期 预后 

分 类 号：R743[医药卫生—神经病学与精神病学]