银杏二萜内酯葡胺注射液治疗急性脑梗死的临床疗效观察及对血Fib和CPR的影响  

Clinical observation of ginkgo diterpene lactone glucosamine injection in the treatment of acute cerebral infarction and its effect on blood Fib and CPR

作　　者：李锐[1] 李昱 LI Rui;LI Yu(Department of Neurology,Anshan Changda Hospital,Anshan,Liaoning,114000,China;Department of Endocrinology,The First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning,116000,China)

机构地区：[1]鞍山市长大医院神经内科,辽宁鞍山114000 [2]大连医科大学附属第一医院内分泌科,辽宁大连116000

出　　处：《当代医学》2021年第11期1-3,共3页Contemporary Medicine

基　　金：国家自然科学基金项目(81700726)。

摘　　要：目的分析银杏二萜内酯葡胺注射液治疗急性脑梗死的临床疗效及对血纤维蛋白原(Fib)、C反应蛋白(CRP)的影响。方法选取2018年11月至2019年11月本院收治的75例急性脑梗死患者为研究对象,采用抽签法分为参照组(n=38)与实验组(n=37)。参照组采用常规治疗,实验组在参照组基础上采用银杏二萜内酯葡胺注射液治疗,比较两组临床治疗效果、神经功能改善状况、治疗前后Fib与CRP水平。结果实验组治疗优良率(94.59%)明显高于参照组(76.32%)(P<0.05)。治疗后,实验组美国国立卫生研究院脑卒中量表(NIHSS)评分明显低于参照组(P<0.05)。治疗前,两组Fib、CRP水平比较差异无统计学意义;治疗后,实验组Fib、CRP水平显著低于参照组(P<0.05)。结论在常规治疗条件下,予以急性脑梗死患者银杏二萜内酯葡胺注射液,可强化临床治疗效果,促进神经功能恢复,改善Fib、CRP水平,值得临床应用。Objective To analyze the clinical efficacy of ginkgo diterpene lactone glucosamine injection in the treatment of acute cerebral infarction and its effect on fibrinogen(Fib)and C-reactive protein(CRP).Methods 75 patients with acute cerebral infarction in our hospital from November 2018 to November 2019 were selected as the research subjects,they were divided into the reference group(n=38)and the experimental group(n=37)by the method of lottery.The reference group was treated with routine treatment,and the experimental group was treated with ginkgo diterpene lactone glucamine injection on the basis of the reference group.The clinical treatment effect,neurological function improvement,FIB and CRP levels before and after treatment were compared between the two groups.Results The excellent treatment rate in the experimental group(94.59%)was significantly higher than that in the reference group(76.32%)(P<0.05).After treatment,the national institutes of health stroke scale(NIHSS)score in the experimental group was significantly lower than that in the reference group(P<0.05).Before treatment,there was no significant difference in Fib and CRP levels between the two groups;after treatment,Fib and CRP levels in the experimental group were significantly lower than those in the reference group(P<0.05).Conclusion Ginkgo diterpene lactone glucosamine injection in patients with acute cerebral infarction under conventional treatment conditions can strengthen the clinical treatment effect,promote its neurological recovery,and improve its Fib and CRP levels.It is worth applying.

关 键 词：急性脑梗死 银杏二萜内酯葡胺注射液 血纤维蛋白原 C反应蛋白 

分 类 号：R743.33[医药卫生—神经病学与精神病学]