桃金娘果实的化学成分研究  

Chemical constituents in fruits of Rhodomyrtus tomentosa

作　　者：于欢 胡雪纯 张冬丽 李敏 许嵘 唐生安 YU Huan;HU Xue-chun;ZHANG Dong-li;LI Min;XU Rong;TANG Sheng-an(Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics(Theranostics),School of Pharmacy,Tianjin Medical University,Tianjin 300070,China;School of Pharmacy,Quanzhou Medical College,Quanzhou 362011,China)

机构地区：[1]天津医科大学药学院,天津市临床药物关键技术重点实验室,天津300070 [2]泉州医学高等专科学校药学院,福建泉州362011

出　　处：《中草药》2021年第5期1252-1257,共6页Chinese Traditional and Herbal Drugs

基　　金：天津市教委科研计划项目(2019ZD031);泉州市科技计划项目(2018N111S)。

摘　　要：目的研究桃金娘Rhodomyrtus tomentosa果实的化学成分。方法采用硅胶柱色谱、SephadexLH-20凝胶柱色谱及半制备高效液相色谱法进行分离纯化,采用NMR和MS等波谱学方法鉴定单体化合物的结构。结果从桃金娘果实95%乙醇提取物的醋酸乙酯萃取部位分离得到9个化合物,分别鉴定为桃金娘酚A(1)、piceatannol4′-O-(6″-O-galloyl)-β-D-glucopyranoside(2)、白皮杉醇(3)、piceatannol glucoside(4)、scirpusin B(5)、杨梅素(6)、杨梅苷(7)、杨梅素-3-O-α-L-呋喃阿拉伯糖苷(8)、没食子酸(9)结论化合物1为新化合物,化合物2、5为首次从该植物中分离得到。Objective To study on the chemical constituents from the fruit of Taojinniang(Rhodomyrtus tomentosa).Methods The chemical constituents were separated and purified by Sephadex LH-20,silica gel,semi-prepared HPLC,and other chromatography techniques.Their structures were elucidated by their physicochemical properties and NMR data.Results Nine compounds(1—9)were isolated,and were identified as tomentosene A(1),piceatannol 4′-O-(6″-O-galloyl)-β-D-glucopyranoside(2),piceatannol(3),piceatannol glucoside(4),scirpusin B(5),myricetin(6),myricitrin(7),myricetin-3-O-α-L-furanoarabinoside(8),and gallic acid(9).Conclusion Compound 1 is a new compound,Compounds 2 and 5 are isolated from this plant for the first time.

关 键 词：桃金娘 桃金娘酚A 白皮杉醇 scirpusin B 杨梅素 没食子酸 

分 类 号：R284.1[医药卫生—中药学]