单纯喉部分切除术治疗喉癌患者的临床效果及对生存率、QOL评分的影响  

Effect of Partial Laryngectomy Alone for Patients with Laryngeal Carcinoma and Its Effect on Survival Rate and QOL Score

作　　者：王美熠[1] WANG Meiyi(Zhongshan Hospital Affiliated to Dalian University,Dalian 116001,China)

机构地区：[1]大连大学附属中山医院,辽宁大连116001

出　　处：《中国医学创新》2021年第8期69-72,共4页Medical Innovation of China

摘　　要：目的:探讨单纯喉部分切除术治疗喉癌患者的临床效果及对生存率、生活质量(QOL)评分的影响。方法:选取2014年4月-2015年4月本院收治的喉癌患者66例,按随机数字表法将其分为研究组和对照组,各33例。对照组给予喉部全切手术治疗,研究组给予单纯喉部分切除术治疗。比较两组临床疗效、术后QOL评分、并发症发生情况和3、5年生存率及复发率。结果:研究组术后QOL各项评分均高于对照组(P<0.05);研究组治疗总有效率高于对照组(P<0.05)。研究组感染与咽瘘发生率均低于对照组,且3、5年生存率均高于对照组(P<0.05)。两组3、5年复发率比较,差异均无统计学意义(P>0.05)。结论:单纯喉部分切除术可提升喉癌患者治疗效果,减少并发症发生,有利于进一步延长患者的存活期,改善术后生活质量,可推广使用。Objective:To investigate the clinical effect of partial laryngectomy alone for patients with laryngeal carcinoma and its effect on survival rate and quality of life(QOL)score.Method:A total of 66 patients with laryngeal carcinoma treated in our hospital from April 2014 to April 2015 were selected.They were divided into study group and control group according to random number table method,with 33 cases in each group.The control group was treated with total laryngectomy,and the study group was treated with partial laryngectomy alone.The treatment effect,postoperative QOL score,incidence of complications,3 and 5 years survival rates and recurrence rates were compared between the two groups.Result:The postoperative all QOL scores of the study group were higher than those of the control group(P<0.05).The total effective rate of the study group was higher than that of the control group(P<0.05).The incidence of infection and pharyngeal fistula in the study group were lower than those in the control group,and the 3 and 5 years survival rates were higher than those in the control group(P<0.05).There was no significant difference in 3 and 5 years recurrence rates between the two groups(P>0.05).Conclusion:Partial laryngectomy alone can improve the treatment effect of patients with laryngeal cancer,reduce the incidence of complications,help to further extend the survival time of patients,improve the quality of life after surgery,and can be popularized.

关 键 词：单纯喉部分切除术 喉癌 生活质量 

分 类 号：R739.65[医药卫生—肿瘤]