Inflammation-based Glasgow prognostic score as an independent prognostic factor in patients with angioimmunoblastic T-cell lymphoma  

作　　者：Guan-Jun Chen Zhi-Jun Wuxiao Yang Liang Chun Li Bi-Bo Fu Hua Wang 

机构地区：[1]Department of Hematological Oncology,Sun Yat-sen University Cancer Center,State Key Laboratory of Oncology in South China,Collaborative Innovation Center for Cancer Medicine,Guangzhou,Guangdong 510060,China [2]Department of Hematologic Oncology,The First Affiliated Hospital,Hainan Medical University,Haikou,Hainan 570102,China

出　　处：《Chinese Medical Journal》2021年第5期579-581,共3页中华医学杂志（英文版）

基　　金：This work was supported by the National Natural Science Foundation of China(No.81700148);a PhD Start-up Fund of Natural Science Foundation of Guangdong Province(No.2017A030310193).

摘　　要：Angioimmunoblastic T-cell lymphoma(AITL)is an aggressive form of peripheral T-cell lymphoma(PIT)associated with poor prognosis.It is characterized by lymph node enlargement,B symptoms(unexplained recurrent fevers(often above 38℃),night sweats,and unexplained weight loss of more than 10%within 6 months),polyclonal hypergammaglobulinemia,and autoimmune hemolysis.[1] C-reactive protein(CRP)synthesized by hepatocytes is an acute-phase protein and an important marker of systemic inflammation.Serum CRP level is not only an independent prognostic factor in Hodgkin lymphoma but also an important independent predictor of AITL.

关 键 词：LYMPHOMA GLASGOW BLASTIC 

分 类 号：R733.1[医药卫生—肿瘤]