单次亚麻醉剂量氯胺酮对乳腺癌根治患者术后早期情绪及恢复质量的影响  

Effects of single sub-narcotic dose of ketamine on mood and recovery quality in breast cancer patients on early postoperative of radical mastectomy

作　　者：杨爱民 余旸[1] 王宏伟[1] 杨磊[1] YANG Aimin;YU Yang;WANG Hongwei(The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)

机构地区：[1]郑州大学第一附属医院,郑州450000

出　　处：《国际精神病学杂志》2021年第1期122-124,共3页Journal Of International Psychiatry

摘　　要：目的探讨乳腺癌根治患者采用单次亚麻醉剂量氯胺酮对术后早期情绪及恢复质量的影响。方法纳入2018年9月~2019年9月期间我院接诊的120例乳腺癌患者作为本次研究对象,掷币法将其分为两组,两组患者均行乳腺癌根治术,均在同样的麻醉方法下进行手术,对照组60例患者术后镇痛予以单纯静脉镇痛泵,观察组60例患者术后镇痛予以单次亚麻醉剂量氯胺酮+静脉镇痛泵,比较两组患者术后早期焦虑、抑郁情绪评分、疼痛评分及恢复质量评分。结果术后第3天,观察组患者焦虑自评量表(SAS)评分及抑郁自评量表(SDS)评分均明显降低,且低于对照组,焦虑,抑郁情绪病例数也明显少于对照组(P<0.05);观察组身体舒适度、情绪状态、心理支持及疼痛评分及总分均高于对照组(P<0.05)。结论单次亚麻醉剂量氯胺酮能快速改善围术期乳腺癌患者术后早期的焦虑、抑郁情绪,提高患者术后恢复质量。Objective To explore the effect of single sub-anaesthetic dose of ketamine on mood and recovery quality in breast cancer patients on early postoperative of radical mastectomy.Methods A total of 120 breast cancer patients admitted to our hospital from September 2018 to September 2019 were included and divided into two groups by the coin toss method.Both groups of patients were planned to do radical breast cancer surgery.The operation was performed under the same anesthesia method.60 patients in the control group were given a simple intravenous analgesia pump for postoperative analgesia,and 60 patients in the observation group were given a single sub-narcotic dose of ketamine+intravenous analgesia for postoperative analgesia.Patient anxiety,depression score,pain score and recovery quality score.Results After 3 day of operation,the SAS score and SDS score of the observation group were significantly lower than those of the control group,and the number of anxiety and depression cases was less than the control group(P<0.05).The body comfort and emotion of the observation group,the state of psychological support,pain score were higher than those in the control group(P<0.05).Conclusion A single sub-anaesthetic dose of ketamine can quickly improve the early anxiety and depression of in breast cancer patients on early postoperative of radical mastectomy,improve their anxiety,depression and quality of postoperative recovery.

关 键 词：乳腺癌 单次亚麻醉剂量 氯胺酮 抑郁 恢复质量 

分 类 号：B749.2[哲学宗教—外国哲学]