基于CiteSpace的金匮肾气丸文献计量研究与可视化分析  

Bibliometric Study and Visual Analysis of Jinkui Shenqi Pills Based on CiteSpace

作　　者：阮蓓蓓 王东军 余静寅 关媛媛 李斌斌 RUAN Beibei;WANG Dongjun;YU Jingyin;GUAN Yuanyuan;LI Binbin

机构地区：[1]台州学院医学院附属市立医院,浙江台州318000 [2]天津中医药大学,天津301617 [3]北京中医药大学东方学院,河北廊坊065000

出　　处：《新中医》2021年第6期10-16,共7页New Chinese Medicine

基　　金：天津中医药大学研究生科研创新项目(YJSKC-20191016);浙江省自然基金资助项目(LY16H270008)。

摘　　要：目的:以金匮肾气丸为研究主题进行文献计量与可视化分析,探索金匮肾气丸研究领域近10年的发展状况及研究热点。方法:对中国知网数据库(CNKI) 2010年1月1日—2019年12月31日相关文献进行检索,应用NoteExpress文献管理软件进行频次分析与文献计量学分析。应用CiteSpace 5.6软件对相关文献进行关键词共现分析、研究机构共现分析,并绘制金匮肾气丸研究领域可视化知识图谱。结果:共纳入849篇文献,通过计量分析找到该领域研究的高产机构、具有代表性的研究团队及具有代表性的研究者。张先庚发表12篇文献,是发文量最高的作者;成都中医药大学发文19篇,是最高产的研究机构;《河南中医》载文26篇,是载文最高的学术期刊;金匮肾气丸是最高频的关键词,且中心性最高;金匮肾气丸关键词聚类分析形成了11个聚类标签,聚类较为合理。通过关键词突现词分析能较好分析该研究的热点和前沿。结论:中西医结合治疗常见糖尿病、糖尿病肾病、骨质疏松、支气管哮喘、慢性心衰的临床研究是当前临床研究热点;应用代谢组学技术进行金匮肾气丸抗氧化、抗衰老的机制研究是当前实验研究的热点;今后可结合现代化研究方法,加强发展以网络药理学、代谢组学技术进行中医药现代化研究,积极部署科研团队进行经方研发工作为未来研究的重点。Objective: To carry out bibliometric study and visual analysis of Jinkui Shenqi pills, and to explore the development status and hotspots of the study of Jinkui Shenqi pills in the past decade. Methods:Relevant literature from January 1, 2010 to December 31, 2019 was searched in the China National Knowledge Infrastructure(CNKI). Frequency analysis and bibliometric analysis were performed with the application of literature management software, Noteexpress. Keyword co-occurrence analysis and institution co-occurrence analysis were carried out by Cite Space 5.6. A visual knowledge map in the research field of Jinkui Shenqi pills was drawn. Results:A total of 849 literature was included to find productive institutions,representative research teams,and representative researchers in this field by bibliometric analysis.ZHANG Xiangeng, the most productive researchers, published 12 articles. Chengdu University of Traditional Chinese medicine,the most productive institution,published 19 articles. Henan Traditional Chinese Medicine published 26 articles and topped in the number of published articles. Jinkui Shenqi pill was the keyword with the highest frequency and the highest centrality. The keyword Jinkui Shenqi pills formed 11 cluster labels with reasonable clustering. The research hotspots and fronts could be better analyzed by analysis of prominent keywords. Conclusion:At present,clinical research hotspots are integrative Chinese medicine and western medicine treatment of common diabetes mellitus, diabetic nephropathy,osteoporosis,bronchial asthma,and chronic heart failure. Besides,the current focus of experimental research is the study on antioxidant and anti-aging mechanism of Jinkui Shenqi pills with the application of metabolomics technology. In the future, in combination with modern research methods, researchers can promote the study of modernization of Chinese medicine with network pharmacology and metabolomics technologies. Besides, the research and development of classic prescription should be the focus of futu

关 键 词：金匮肾气丸 CITESPACE 可视化分析 知识图谱 研究热点 

分 类 号：R229[医药卫生—中医基础理论]