Symbiotic bacteria attenuate Drosophila oviposition repellence to alkaline through acidification  

作　　者：Wei Liu Jie Wang Hong-Yu Zhang Ying-Chun Yang Ru-Xue Kang Peng Bai Hui Fu Li-Rong Chen Yan-Ping Gao Eng King Tan 

机构地区：[1]Department of Medical Laboratory Science,Fenyang College,Shanxi Medical University,Shanxi,China [2]Department of Neurology,National Neuroscience Institute,Singapore General Hospital Campus,Singapore [3]Department of Basic Medical,Fenyang College,Shanxi Medical University,Shanxi,China

出　　处：《Insect Science》2021年第2期403-414,共12页昆虫科学（英文版）

基　　金：We would like to thank all members of Liu Weis lab for helpful discussions.This work was supported by the National Natural Science Foundation of China(31501175);Grants of Shanxi Medical University Fenyang College(2018C02);Shanxi Undergraduate Training Program for Innovation and Entrepreneurship(2019819).

摘　　要：Metazoans harbor a wealth of symbionts that are ever-changing the environment by taking up resources and/or excreting metabolites.One such common environmental modification is a change in pH.Conventional wisdom holds that symbionts facilitate the survival and production of their hosts in the wild,but this notion lacks empirical evidence.Here,we report that symbiotic bacteria in the genus Enterococcus attenuate the oviposition avoidance of alkaline environments in Drosophila.We studied the effects of alkalinity on oviposition preference for the first time,and found that flies are robustly disinclined to oviposit on alkali-containing substrates.This innate repulsion to alkaline environments is explained,in part,by the fact that alkalinity compromises the health and lifespan of both offspring and parent Drosophila.Enterococcus dramatically diminished or even completely reversed the ovipositional avoidance of alkalinity in Drosophila.Mechanistically,Enterococcus generate abundant lactate during fermentation,which neutralizes the residual alkali in an egg-laying substrate.In conclusion,Enterococcus protects Drosophila from alkali stress by acidifying the ovipositional substrate,and ultimately improves the fitness of the Drosophila population.Our results demonstrate that symbionts are profound factors in the Drosophila ovipositional decision,and extend our understanding of the intimate interactions between Drosophila and their symbionts.

关 键 词：ACIDIFICATION ALKALINE Drosophila Enterococcus FITNESS OVIPOSITION 

分 类 号：Q96[生物学—昆虫学]