抑郁症伴慢性疼痛与基因多态性相关性的研究进展  

Research progress on the relationship between depression with chronic pain and gene polymorphism

作　　者：穆卡代斯·赛达合买提 邹韶红[2] 胡曼娜[2] Mukadaisi·Saidahemaiti;Zou Shaohong;Hu Manna(Xinjiang Medical University,Urumqi 830001,China;Department of Clinical Psychology,People's Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830001,China)

机构地区：[1]新疆医科大学,乌鲁木齐830001 [2]新疆维吾尔自治区人民医院临床心理科,乌鲁木齐830001

出　　处：《神经疾病与精神卫生》2021年第2期104-107,共4页Journal of Neuroscience and Mental Health

摘　　要：抑郁症作为精神科常见的疾病,具有高发病率、高复发率、高致残率等特点。流行病学调查显示抑郁症常与慢性疼痛伴随,而慢性疼痛也可能导致抑郁的发生。近年来的研究进一步从基因多态性方面发掘抑郁症及慢性疼痛发生、发展相关的机制,为伴慢性疼痛的抑郁症的诊断及治疗提供有效证据。现旨对近年来有关抑郁症伴慢性疼痛与基因多态性相关性研究进行归纳总结。Depression is a common disease in psychiatric department,and has high incidence rate,high recurrence rate and high disability rate.Epidemiological investigation shows that depression is often accompanied by chronic pain,which may also lead to depression.In recent years,studies have further explored the mechanism related to the occurrence and development of depression and chronic pain from the perspective of gene polymorphism,which provides effective evidence for the diagnosis and treatment of depression with chronic pain.This paper aims to summarize the research progress on the correlation between depression with chronic pain and gene polymorphism in recent years.

关 键 词：抑郁症 慢性疼痛 多态性 单核苷酸 综述 

分 类 号：R749.4[医药卫生—神经病学与精神病学]