同时性双侧原发乳腺癌的危险因素与预防  

Risk factors and prevention of synchronous bilateral breast cancer

作　　者：姚玲莉 王金秋 叶丹 郭宇[2] Yao Lingli;Wang Jinqu;Ye Dan;Guo Yu(Graduate School,Ningbo Uinirersily School of Medicine,Ningbo 315211,China;Department of Thyroid and Breast Surgery,Ningbo First Hospital,Ningbo 315010,China)

机构地区：[1]宁波大学医学院研究生院,315211 [2]宁波市第一医院甲乳外科,315010

出　　处：《国际外科学杂志》2021年第3期194-198,共5页International Journal of Surgery

摘　　要：同时性双侧原发乳腺癌是指两侧乳腺同步发生原发肿瘤.总体发病率较低但近年来随着隐匿型乳腺癌的发现增加,其总体呈上升趋势。同时性双侧原发乳腺癌的发病机制尚未明确,老龄、-级乳腺癌家族史.癌前病变硬化性腺病与首发癌病理特点是目前认可的危险因素。与单侧乳腺癌相比,同时性双侧原发乳腺癌预后不佳。应增强高风险女性风险意识,定期检查,尽早发现非触及病灶。通过对高风险单侧乳腺癌患者采取各项预防性治疗,可有效减少乳腺癌事件.改善患者预后。本文通过回顾国内外文献,阐述同时性双侧原发乳腺癌的危险因素、病理组织学特征、预后和预防性治疗等。Synchronous bilateral primary breast cancer refers to the simulaneous oceurrence of primary cancers in both breasts.The overall morbidity is low.However,with the detection of occult breast cancer inereasing recently,it shows an upward trend.The pathogenesis is not yet clear,old age.family history of primary breast cancer,sclerosing adenopathy of precancerous lesions and pathological characteristics of first cancer are urently recognized risk factors.Compared with unilateral breast eancer,prognosis for synchronous bilateral primary breast cancer is poor.Raise the risk awareness of high-risk women,check regularly to find non-palpable lesions as soon as possible.By taking various preventive treatments for patients with high-risk unilateral breast eanecer,the incidence of breast cancer can be efctively reduced and the prognosis of putients can be improwed.By reviewing the literature at home and abroad,it systematically expounds the risk factors.histopathological features.prognosis and preventive treatment of synchronous bilateral breast cancer.

关 键 词：乳腺肿瘤:同时性双侧乳腺癌 危险因素:病理 预防与控制 

分 类 号：R737.9[医药卫生—肿瘤]