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作 者:张永贞[1] 高秋生 崔王飞 曹凌[1] 郭雪蓉[1] 马朝辉[1] 王昕琛[1] 苏芳[1] 乔楠 张瑞锋[1] 王媛[1] 王新正[3] 张桓虎 ZHANG Yong-zhen;GAO Qiu-sheng;CUI Wang-fei;CAO Ling;GUO Xue-rong;MA Zhao-hui;WANG Xin-chen;SU Fang;QIAO Nan;ZHANG Rui-feng;WANG Yuan;WANG Xin-zheng;ZHANG Huan-hu(Shanxi Cancer Hospital/Institute,Taiyuan 030013,China;Yangquan Institute of Cancer Prevention and Treatment,Yangquan 045000,China;Yangcheng County Cancer Hospital,Yangcheng 048100,China)
机构地区:[1]山西省肿瘤医院/肿瘤研究所,山西太原030013 [2]阳泉市肿瘤防治研究所,山西阳泉045000 [3]阳城县肿瘤医院,山西阳城048100
出 处:《中国肿瘤》2021年第2期131-136,共6页China Cancer
摘 要:[目的]分析山西省2014—2018年城市癌症早诊早治项目的癌症筛查结果。[方法]采取整群随机抽样的方法,选取太原市、阳泉市、晋城市40~74岁常住居民进行患癌风险评估,评估出的高风险对象免费接受相应癌种的临床筛查,分析评估各癌种的高风险率、筛查顺应性和阳性病变检出率。[结果]研究人群整体患癌高风险率为41.37%,其中男性高风险率高于女性,55~59岁人群高风险率最高,各癌种高风险率从高到低依次为:上消化道癌22.46%,肺癌19.94%,乳腺癌17.38%,结直肠癌12.24%,肝癌9.42%;各癌种筛查顺应性从高到低为:乳腺癌(51.33%)、肝癌(43.74%)、肺癌(34.41%)、结直肠癌(21.71%)、上消化道癌(14.53%);临床筛查结果显示,肺癌、上消化道癌和结直肠癌的阳性病变检出率随年龄的增加而增高,45~49岁女性乳腺癌阳性病变检出率较高,男性上消化道癌和结直肠癌的阳性病变检出率高于女性。[结论]人群患癌高风险比例分布与当地癌症发病分布基本一致,筛查顺应性和筛查方法相关,介入性检查顺应性较低。筛查人群高风险率、顺应性以及阳性病变检出率不同性别和不同年龄段存在一定的差异,有针对性地对城市高风险人群进行筛查,能够发现早期癌症患者,从长远来讲将有效降低癌症的发病率和死亡率。[Purpose] To analyze the results of cancer screening from 2014 to 2018 in Shanxi Province.[Methods] Using cluster random sampling method,residents of 40 ~74 years old in Taiyuan,Yangquan,and Jincheng were selected for cancer risk assessment. The identified high-risk subjects received clinical screening for the corresponding cancers. The high risk rate,screening compliance,and positive lesion detection rate were analyzed. [Results]The overall high-risk rate of cancer in the study population was 41.37%,the high-risk rate of men was higher than that of women,and the risk rate of cancer age group 55 ~59 years was the highest. The high-risk rates of upper gastrointestinal cancer,lung cancer,breast cancer,colorectal cancer and liver cancer were 22.46%19.94% 17.38%,12.24% and 9.42%,respectively. The screening compliance of breast cancer,liver cancer,lung cancer,colorectal cancer and upper digestive tract cancer was 51.33%,43.74%,34.41%,21.71% and 14.53%,respectively. Clinical screening results showed that the detection rate of positive lesions of lung cancer,upper digestive tract cancer and colorectal cancer increased with age,and the detection rate of breast cancer positive lesions in women aged 45 ~49 years was higher. In addition,the detection rate of positive lesions of upper digestive tract cancer and colorectal cancer in men was higher than that in women. [Conclusion] The distribution of high risk population of cancer is basically consistent with the local cancer incidence. Screening compliance is related to screening methods,and compliance of screening with invasive examination is low. The high-risk rate,compliance,and positive lesion detection rate of the screening population are different between different gender and different age groups. Screening for high-risk populations can find out early cancer patients to reduce long-term cancer morbidity and mortality.
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