癫痫患者撤药及撤药后复发的研究进展  

Research progress of drug-withdrawal and relapse in epileptic patients

作　　者：徐寿成 狄晴[1] XU Shou-cheng;DI Qing(Department of Neurology,Brain Hospital Affiliated to Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京医科大学附属脑科医院神经内科,210029

出　　处：《临床神经病学杂志》2021年第2期153-157,共5页Journal of Clinical Neurology

摘　　要：药物治疗目前仍是癫痫患者治疗的主要手段,癫痫达一定时间无发作,患者和家属首先考虑的是撤药问题,但临床工作中癫痫患者的撤药管理仍存在许多亟待解决的问题。本文对临床达一定缓解期癫痫患者撤药的时机、撤药速度、方法、影响撤药后复发的因素、撤药后复发患者的处理及其预后等焦点问题近年来的进展作一综述,以供临床医生和今后研究参考。Drug therapy is still the main treatment for patients with epilepsy at present.Anti-epileptic drugs withdrawal will be considered by the patients and their family members when they achieved seizure freedom.However,there are still many problems to be solved in the management of anti-epileptic drugs withdrawal in clinical work.This article reviews the recent progress in the timing,speed and methods of drug-withdrawal,the factors influencing the recurrence after drug-withdrawal,the prognosis and management of patients with epilepsy recurrence.It would provide a foundation for the more standardized clinical treatment and further research.

关 键 词：癫痫 抗癫痫药物 撤药 复发 危险因素 预后 

分 类 号：R742.1[医药卫生—神经病学与精神病学]