T淋巴细胞亚群在炎症性肠病中作用的研究  

T lymphocyte subsets in inflammatory bowel disease

作　　者：徐振江 徐洪雨[1] XU Zhenjiang;XU Hongyu(Department of Gastroenterology,the First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)

机构地区：[1]哈尔滨医科大学附属第一医院消化内科,黑龙江哈尔滨150001

出　　处：《胃肠病学和肝病学杂志》2021年第4期454-458,共5页Chinese Journal of Gastroenterology and Hepatology

摘　　要：炎症性肠病(inflammatory bowel disease,IBD)主要包括溃疡性结肠炎(ulcerative colitis,UC)和克罗恩病(Crohn’s disease,CD),是一种反复发作的慢性炎症性肠道疾病,通常认为IBD的发生、发展与自身免疫系统异常关系密切。胃肠道需要在耐受内容物及对病原体的免疫之间保持微妙的平衡,T淋巴细胞亚群在其过程中发挥重要的作用。本文回顾了近年来T淋巴细胞亚群在IBD发生、发展过程中作用的研究,及其对于新治疗方案的指导。Inflammatory bowel disease(IBD),including ulcerative colitis(UC)and Crohn’s disease(CD),is a recurrent chronic inflammatory bowel disease,which is generally considered the occurrence and development of IBD are closely related to the abnormalities of the autoimmune system.The gastrointestinal tract needs to maintain a delicate balance between tolerance to content and immunity to pathogens,and T lymphocyte subsets play an important role in this process.This article reviewed recent studies on the role of T lymphocyte subsets in the occurrence and development of chronic inflammation in IBD,and its guidance for new treatment options.

关 键 词：炎症性肠病 T淋巴细胞亚群 炎症细胞因子 

分 类 号：R574.62[医药卫生—消化系统]