Skeletal muscle metastases of hepatocellular carcinoma: A case report and literature review  

作　　者：Qi Song Xiao-Feng Sun Xiao-Li Wu Yi Dong Le Wang 

机构地区：[1]Department of Ultrasound,Bethune First Hospital of Jilin University,Changchun 130000,Jilin Province,China

出　　处：《World Journal of Clinical Cases》2021年第14期3334-3341,共8页世界临床病例杂志

摘　　要：BACKGROUND The metastasis of liver cancer to skeletal muscle is extremely rare compared to other sites.We herein report a case of rapidly developing skeletal metastases following liver transplantation due to primary liver cancer.CASE SUMMARY A 70-year-old male with underlying chronic hepatitis B virus infection was diagnosed with hepatocellular carcinoma(HCC),for which he underwent liver transplantation in 2014.Six years after receiving the transplant,pathological examination confirmed the presence of HCC without vascular invasion.He was admitted to the hospital with a rapidly growing mass on his right thigh.Ultrasound examination revealed a mixed echo mass in the lateral soft tissue of the middle part of the right femur.Magnetic resonance imaging showed heterogeneous iso-signal intensity on T1-weighted images and heterogeneous hyper-intensity on T2-weighted images compared to the surrounding muscles.Pathological examination of the ultrasound-guided needle biopsy specimen revealed that it was similar to the previously detected liver cancer;the diagnosis was metastasis of HCC.Surgical excision was performed.There were no other sites of metastasis,and the patient recovered well after surgery.CONCLUSION This report presents a rare case of skeletal metastasis following liver transplantation for HCC.The study suggests a possible role for skeletal muscle metastasis mechanisms,which should be the focus of future research.

关 键 词：Hepatocellular carcinoma TRANSPLANT Skeletal muscle metastasis PATHOLOGICAL Case report 

分 类 号：R735.7[医药卫生—肿瘤]