青年脑出血病因及高危因素分析  

Etiology and risk factors of cerebral hemorrhage in young people

作　　者：燕鹏 李倩 覃成箭[2] 郑传华 蓝川琉 吕浩 梁洪岖 罗起胜[2] Yan Peng;Li Qian;Qin Chengjian;Zheng Chuanhua;Lan Chuanliu;Lyu Hao;Liang Hongqu;Luo Qisheng(Graduate School,Youjiang Medical University for Nationalities,Baise 533000,Guangxi,China;Neurosurgery Intensive Care Unit,the Affiliated Hospital of Youjiang Medical University for Nationalities,Baise 533000,Guangxi,China)

机构地区：[1]右江民族医学院研究生学院,广西百色533000 [2]右江民族医学院附属医院神经外科重症监护病房,广西百色533000

出　　处：《右江民族医学院学报》2021年第2期186-191,195,共7页Journal of Youjiang Medical University for Nationalities

基　　金：国家自然科学基金项目(81760450)。

摘　　要：目的分析和探讨青年人脑出血的病因及高危因素,为青年脑出血患者的个体化诊疗方案的制定提供理论基础。方法收集右江民族医学院附属医院2014—2019年收治的18~45岁青年脑出血患者相关信息,按照年龄划分为3组,根据欧洲SMASH-U脑出血分型对入选资料行病因及危险因素相关分析。结果542例病例中,高血压病301例(55.54%),脑血管畸形72例(13.28%),系统性疾病34例(6.27%),药物因素5例(0.92%),原因不明130例(23.99%)。18~29岁组在高血压病、脑血管畸形、不明原因类型中与其余两组差异具有统计学意义(P<0.01),在系统性疾病类型中与40~45岁组差异具有统计学意义(P<0.01)。高危因素前5位依次为高血压病(60.70%)、饮酒(42.62%)、吸烟(36.53%)、血脂异常(30.07%)、肥胖(23.43%),18~29岁组与40~45岁组5种高危因素差异均有统计学意义(P<0.01),18~29岁组与30~39岁组在高血压病、饮酒、吸烟中差异具有统计学意义(P<0.01);30~39岁组与40~45岁组在高血压病中的差异具有统计学意义(P<0.01)。结论高血压型脑出血是青年脑出血最常见类型,其次依次为病因不明型、颅内血管结构异常、系统性疾病、药物因素。高血压病、饮酒、吸烟、血脂异常、肥胖等都是青年脑出血常见的高危因素。Objective To explore the etiology and high risk factors of cerebral hemorrhage in young people,so as to provide a theoretical basis for the formulation of individualized diagnosis and treatment programs for young patients with cerebral hemorrhage.Methods This study collected relevant information of young patients with cerebral hemorrhage,who aged 18~45 years old and were admitted to the Affiliated Hospital of Youjiang Medical University for Nationalities from 2014 to 2019.They were divided into 3 groups according to their ages.The correlation analysis of etiology and risk factors was conducted according to the European SMASH-U classification of cerebral hemorrhage.Results Among 542 cases,there were 301 cases of hypertension(55.54%),72 cases of cerebrovascular malformations(13.28%),34 cases of systemic diseases(6.27%),5 cases of drug factors(0.92%),and 130 cases of unknown causes(23.99%).There were statistically significant differences in types of hypertension,cerebrovascular malformation and unknown causes between the 18~29 years old group and the other two groups(P<0.01).The 18~29 years old group was significantly different from the 40~45 years old group in types of systemic diseases(P<0.01).The top five risk factors were hypertension(60.70%),drinking(42.62%),smoking(36.53%),dyslipidemia(30.07%)and obesity(23.43%).There were statistically significant differences in the five risk factors between the 18~29 years old group and the 40~45 years old group(P<0.01),and significant differences were also found in hypertension,drinking and smoking between the 18~29 years old group and the 30~39 years old group(P<0.01).The difference in hypertension between the 30~39 years old group and the 40~45 years old group was statistically significant(P<0.01).Conclusion Hypertensive cerebral hemorrhage is the most common type of cerebral hemorrhage in young people,followed by unknown etiology,abnormalities of intracranial vascular structure,systemic diseases,and drug factors.Hypertension,drinking,smoking,dyslipidemia and obesity are

关 键 词：青年 脑出血 病因 高危因素 

分 类 号：R743.34[医药卫生—神经病学与精神病学]