中药单体治疗肝细胞癌的研究  

Study on the Treatment of Hepatocellular Carcinoma with Chinese Medicine Monomer

作　　者：孙莹莹 龚先琼[2] SUN Ying-ying;GONG Xian-qiong(The Second Clinical College of Fujian University of Traditional Chinese Medicine,Fuzhou 351012,Fujian,China;Liver Disease Center,Xiamen Traditional Chinese Medicine Hospital,Fujian University of Traditional Chinese Medicine,Xiamen 361009,Fujian,China)

机构地区：[1]福建中医药大学第二临床医学院,福建福州351012 [2]福建中医药大学附属厦门中医院肝病中心,福建厦门361009

出　　处：《医学信息》2021年第9期33-36,共4页Journal of Medical Information

基　　金：国家自然科学基金青年项目(编号:81600465);福建省自然科学基金面上项目(编号:2019D013)。

摘　　要：肝细胞癌是最具侵袭性的肿瘤之一,是我国最常见的恶性肿瘤及肿瘤致死病因之一,严重威胁患者的健康和生命。近年来的研究表明中药单体可通过多通路抗肝癌细胞增殖、转移及抗肝癌组织血管生成,本文就黄酮类化合物、苷类化合物、生物碱类化合物及其他化合物等中药单体治疗肝细胞癌的相关研究进展作一综述。Hepatocellular carcinoma is one of the most aggressive tumors and one of the most common malignant tumors and tumor death causes in China,which seriously threatens the health and lives of patients.Recent studies have shown that Chinese medicine monomers can resist the proliferation and metastasis of liver cancer cells and the angiogenesis of liver cancer tissues through multiple pathways.This article summarizes the research progress of flavonoids,glycosides,alkaloids and other compounds in the treatment of hepatocellular carcinoma.

关 键 词：肝细胞癌 中药单体 黄酮类 苷类化合物 生物碱类化合物 

分 类 号：R735.7[医药卫生—肿瘤] R730.5[医药卫生—临床医学]