北京市社区居民大肠癌筛查肠道病变影响因素分析  

Analysis of Influencing Factors of Intestinal Lesions in Colorectal Cancer Screening for Residents in Beijing Community

作　　者：肖春丽[1] 游凯[1] 李长青[1] XIAO Chun-li;YOU Kai;LI Chang-qing(Beijing Shunyi District Center for Disease Control and Prevention,Beijing 101300,China)

机构地区：[1]北京市顺义区疾病预防控制中心,北京101300

出　　处：《医学信息》2021年第9期76-80,共5页Journal of Medical Information

摘　　要：目的探讨大肠癌筛查肠道病变的相关因素,为今后制定大肠癌筛查相关防治措施提供科学依据。方法选取2016年3月~2020年12月北京市顺义区40~74岁居民,完成问卷调查与便潜血检查(FOBT)确定大肠癌高危人群,高危人群行全结肠镜检查,分析肠道病变影响因素。结果不同性别、年龄、BMI、吸烟情况、糖尿病情况人群病变检出率比较,差异有统计学意义(P<0.05),不同学历、婚姻状态、肿瘤家族史情况人群病变检出率比较,差异无统计学意义(P>0.05);2879例完成肠镜检查的居民中,755例肠镜检查有病变,进展期腺瘤及以上病变者103例,检出率为3.58%;是否有肠息肉史、慢性阑尾炎或阑尾切除史人群检出率比较,差异有统计学意义(P<0.05);是否有溃疡性结肠炎、克罗恩病、胃十二指肠溃疡、痔疮、慢性腹泻史、慢性便秘史、黏液或者血便史、慢性胆囊炎或胆囊切除史、不良生活事件史、本人癌症史、一级亲属肠癌史及便潜血检查阳性人群检出率比较,差异无统计学意义(P>0.05);多因素Logistic回归分析结果显示,性别、年龄、BMI、慢性阑尾炎或阑尾切除史是肠镜诊断阳性的独立影响因素(P<0.05)。结论北京市顺义区大肠癌筛查病变检出率较高,BMI越高、年龄越大的男性更容易检出肠道病变,此类人群应该作为健康教育工作的重点,动员该类人群参与大肠癌筛查工作的基础上,也应着重培养其健康的生活方式,以降低大肠癌的发病风险。Objective To explore the related factors of colorectal cancer screening for intestinal lesions,and provide scientific basis for the development of related prevention and treatment measures for colorectal cancer screening in the future.Methods From March 2016 to December 2020,residents from 40 to 74 years old in Shunyi District of Beijing were selected to complete a questionnaire and fecal occult blood test(FOBT)to identify high-risk groups of colorectal cancer.High-risk groups underwent colonoscopy to analyze the impact of intestinal lesions factor.Results The difference in the detection rate of lesions among people of different gender,age,BMI,smoking status,and diabetes status was statistically significant(P<0.05).There was no statistically significant difference in the detection rate of lesions among people with different educational backgrounds,marital status,and family history of tumors(P>0.05);Among the 2879 residents who completed colonoscopy,755 had lesions under colonoscopy,103 had advanced adenoma and above,and the detection rate was 3.58%;Whether there was a history of intestinal polyps,chronic appendicitis or history of appendicectomy,the difference was statistically significant(P<0.05);Whether there was ulcerative colitis,Crohn's disease,gastroduodenal ulcer,hemorrhoids,history of chronic diarrhea,history of chronic constipation,history of mucus or blood in the stool,history of chronic cholecystitis or cholecystectomy,history of adverse life events,history of cancer,comparison of the detection rate of people with a history of bowel cancer in first-degree relatives and positive fecal occult blood tests,the difference was not statistically significant(P>0.05);The results of multivariate Logistic regression analysis showed that gender,age,BMI,chronic appendicitis or history of appendectomy were independent influencing factors for positive colonoscopy diagnosis(P<0.05).Conclusion The detection rate of colorectal cancer screening lesions in Shunyi District of Beijing is higher.Men with higher BMI and older

关 键 词：大肠癌筛查 肠道病变 肠镜检查 

分 类 号：R735.34[医药卫生—肿瘤]